新生児の消化性潰瘍

概要

論文の詳細を見る
During the past seventeen years, we have experienced twenty five cases of peptic ulcer disease in neonates at Tokyo Metropolitan Kiyose Childen's Hospital. In eighteen cases (72.0%), initial symptom appeared within forty eight hours after birth, and the majority of babies (72.0%) were healthy fullterm without apparent predisposing factors. The presenting symptoms were hematemesis and melena in fifteen (60.0%), melena in twelve (48.0%), and vomiting in eight (32.0%). Gastric ulcers were multiple, shallow in most of the cases, and the findings were compataible with acute gastric lesions (AGL) or acute gastric mucosal lesions (AGML). Emergency endoscopy was done on 24 cases and was an excellent procedure to define peptic ulcer. Upper gastrointestinal series were performed in 14 cases, but were not valuable for diagnosis except one case. Marked dilatation of the stomach with gastric outlet obstruction was a signifcant radiological finding for suspecting peptic ulcer disease. Feedings following the short period of gastric drainage were well tolerated, and treatment with antacids or H2 antagonist was not necessary if not accompanied with reflux esophagitis.
特定非営利活動法人日本小児外科学会の論文
1990-05-20