BIOLOGICAL EVALUATION OF N-TERMINAL PENTA- AND OCTAPEPTIDES OF NEUROPEPTIDS γ, A HIGHLY POTENT TACHYKININ PEPTIDE

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概要

• 論文の詳細を見る
• 九州大学の論文

著者

• SHIMOHIGASHI Yasuyuki

  Faculty and Graduate School of Sciences, Kyushu University

• Shimohigashi Y

  Kyushu Univ. Fukuoka

• Shimohigashi Yasuyuki

  Laboratory Of Biochemistry Department Of Chemistry Faculty Of Science Kyushu University

• Ohno Motonori

  Laboratory Of Biochemistry Department Of Chemistry Faculty Of Science Kyushu University

• Ohno Motonori

  Faculty Of Science Kyushu University

• Ohno M

  Laboratory Of Biochemistry Department Of Chemistry Faculty Of Science Kyusyu University

• Shimohigashi Yasuyuki

  Laboratory Of Structure-function Biochemistry Department Of Molecular Chemistry Graduate School Of S

• MATSUMOTO Hiroshi

  Laboratory of Biochemistry, Department of Chemistry, Faculty of Science, Kyushu University

• MATSUMOTO Hiroshi

  Faculty of Science, Kyushu University

• Shimohigashi Y

  Laboratory Of Structure-function Biochemistry Faculty And Graduate School Of Science Kyushu Universi

• Shimohigashi Y

  Faculty And Graduate School Of Sciences Kyushu University

• Matsumoto Hideko

  Laboratory Of Cellular Biochemistry Riken (the Institute Of Physical Of Physical And Chemical Resear

• Matsumoto Hiroshi

  Laboratory Of Biochemistry Department Of Chemistry Faculty Of Science Kyushu University

• Matsumoto Hiroshi

  Faculty Of Engineering Shinshu University

関連論文

• Splicing Variants of pdf Gene in the Honeybee Apis mellifera
• Design and Synthesis of α-Helix Peptide Bonding to Prion Protein N-terminal Octarepeat Domain
• Immunological Evidences of Circadian Neuropeptide PDF Isoform Present at the Lamina Outer Cells and Varicose Network in the Optic Lobes of the Cricket Gryllus bimaculatus
• Identification of Novel Isofoms of the Circadian Neuropeptide PDF in the Silk Moth Bombyx mori and their Expression in Brain
• cDNA Cloning and mRNA Expression of the Circadian Neuropeptide PDF in the Silk Moth Bombyx mori
• Structural Analysis and Identification of Novel Isoforms of the Circadian Clock Gene period in the Silk Moth Bombyx mori(Neurobiology)
• cDNA Cloning and Nuclear Localization of the Circadian Neuropeptide Designated as Pigment-Dispersing Factor PDF in the Cricket Gryllus bimaculatus
• Design and Preparation of Universal Anti-PERIOD Antibodies and their Immunoresponses
• Synthesis of Endomorphin-2Analogues Containing Piperidinecarboxylic Acid (Pip) and 2-Azetidinecarboxylic Acid (Aze)
• Synthesis and Biological Activity of Endomorphin-2 Analogues Containing Pro Mimics
• Synthesis and Binding Activities of Endomorphin Analogs Containing 1-Aminocyclopropane-1-carboxylic Acid
• Synthesis and Receptor-Binding Activity of Morphiceptin Analogs Containing α, α-Disubstituted Glycine in the Position 2
• Synthesis and Receptor-binding Activity of Endomorphin Analogs Containing α, α-Disubstituted Glycine
• Molecular Cloning and In Situ Hybridization of Circadian Neuropeptide PDF Receptor in the Fruit Fly Drosophila melanogaster
• Structure-Activity Studies of FMRFamide-Related Peptides in Activating the Specific Receptor Present in the Housefly Musca domestica
• cDNA Cloning of PDF Peptide Precursors in House Fly and Last Summer Cicada
• Chymotrypsin Inhibition Induced by Side Chain-Side Chain Intramolecular CH/π Interaction in D-Thr-L-Phe Benzylamide
• Ligand-inducing Conformation Changes in the Estrogen Receptor C-Terminal Tail Moiety and Their Sensing by Polyclonal Antibodies
• Preparation of the Antibody Which Discriminates the Conformations of Ligand-bound and Ligand-free Estrogen Receptors : Applications to the Quantitative Analysis of Ligand Bindings
• Aggregation Feature of Fluorine-Substituted Benzene Rings and Intermodular C-H…F Interaction: Crystal Structure Analyses of Mono- and Trifluoro-L-phenylalanines
• SOLVENT DEPENDENCE OF THE 1^H-NMR CHEMICAL SHIFTS OF AMIDE PROTONS AND α-PROTONS OF ACYLAMINO ACIDS
• Structural Requirement of Housefly FMRFamide Peptides in Its Receptor Activation
• FMRFamide-Related Peptides in the Nervous System of the Housefly Musca domestica : cDNA Cloning and Actions on Clam Heart Contraction
• INTERACTION OF HIGHLY BIOACTIVE GRAMICIDIN S ANALOG LACKING HYDROPHILIC AMINO ACID RESIDUES WITH BIOMEMBRANES
• Structural Characterization of the Housefly PDF, A Circadian Rhythm Pacemaker Hormone
• The Structure-activity Studies of Drosophila FMRFamide-related Peptides
• Localization Profiles of the Precursor Protein of Circadian Rhythm Pacemaker Hormone PDF in Gryllus Brain
• Structural Analysis of the PERIOD-PAS Domain Binding Regions in Insect Clock Protein TIMELESS
• Double-labelled in situ Hybridization Reveals the Lack of Co-localization of mRNAs for the Circadian Neuropeptide PDF and FMRFamide in Brains of the Flies Musca domestica and Drosophila melanogaster
• IMMUNOCYTO- AND HISTOCHEMICAL ANALYSIS ON THE CIRCADIAN NEUROPEPTIDE PDF IN GRYLLUS BIMACULATUS(Physiology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
• Immunocytochemical Identification the Circadian Neuromodulator PDF in the Housefly Musca domestica : Formation of Mature Peptide
• Immunocytochemical Studies on the Circadian Neuropeptide PDF in the Cricket Gryllus bimaculatus
• Structural Characteristics of Drosophila Estrogen-related Receptor Ligand Binding Domain to Capture the Peptide and Non-peptide Ligands
• LOCALIZATION PROFILES OF ORCADIAN NEUROPEPTIDE PDF IN THE BRAIN OF FLIES, MUSCA DOMESTICA(Physiology,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
• LOCALIZATION PROFILES OF CIRCADIAN NEUROPEPTIDE PDF IN THE BRAIN OF CRICKET, GRYLLUS BIMACULATUS(Physiology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
• Molecular Cogs of the Insect Circadian Clock
• Functional Analysis of F-Domain Peptides Important for the Basal Constitutive Activity of Human Nuclear Receptor
• α-Helix Peptides for Bio-Panning in the Phage Display Method to Obtain the Antibodies Specific for Conformation Change in Nuclear Receptors
• Highly Sensitive Monoclonal Antibodies to Distinguish Conformational Changes Induced by Endocrine Disrupting Chemicals in the Estrogen Receptor
• Specific Affinity Labeling of Cys60 in the δ Opioid Receptor by Npys-containing Dynorphin A Analog
• Differential Receptor Binding Characteristics of the Phenylalanine Residues at Positions 3-4 of Endomorphin-2
• The Role of Deltorphin II Phenylalanine Residue in Binding to the δ Opioid Receptor
• Exploration of the Role of Phenylalanine in the Thrombin Receptor Tethered-Ligand Peptide by Substitution with a Series of Trifluorophenylalanines
• The Mode of Molecular Interation of Phe-3 of Deltorphin II and Endomorphin 2 in Opioid Receptor Binding
• Receptor Interaction Mode of the Phe-phenyl Group of Opioid Peptides
• Exploration of Universal Cysteines in the Bining Sites of Therr Opioid Receptor Subtypes by Disulfide-Bonding Affinty Labeling with Chemically Activated Thiol-Containing Dynorphin A Analogs
• Affinity Labeling of Opioid Receptor Subtypes by Activated Thiol-containig Dynorphin A Analogs
• Different Roles of Two Consecutive Leucine Residues in a Receptor-Tethered Ligand Peptide (SFLLRNP) in Thrombin Receptor Activation
• Placenta Expressing the Greatest Quantity of Bisphenol A Receptor ERRγ among the Human Reproductive Tissues : Predominant Expression of Type-1 ERRγ Isoform
• Direct Measure of Fluorescence Intensity for Efficient Receptor-binding Assay : Conjugates of Ethinylcarboxyestradiol and 5(and 6)-Carboxyfluorescein via α,ω-Diaminoalkanes as a Tracer for Estrogen Receptor
• Differential Receptor Recognition by Dmt-Containing Enkephalin Dimers Cross-Linked by Phenylenediamines
• The Molecular Mechanism of ORL1 Nociceptin Receptor in Activation : Residual Essentials in the Sixth Transmembrane Domain
• Optimization of the N-Terminal Group of Ac-RYYRIK-NH_2 as ORL1 Receptor Antagonist
• The Output Mechanism of Circadian Pacemaker Neuropeptide PDF in the Regulation of Bimodal Locomotor Distribution
• Structural Evidence for Endocrine Disruptor Bisphenol A Binding to Human Nuclear Receptor ERRγ
• Immunological Confirmation of Circadian-Related Neuropeptide PDF-Isoform Peptide in the Cricket Gryllus bimaculatus
• Reversible Affinity Labeling of Opioid Receptors via Disulfide Bonding: Discriminative Labeling of μ and δ Subtypes by Chemically Activated Thiol-Containing Enkephalin Analogs
• Characterization and Application of Monoclonal Antibody Specific for Ser(P)-Gln Phosphorylation Motif
• Monoclonal Antibody Sensing Assay for Conformation Change Induced by Metal Binding to Prion Protein N-Terminal Octarepeat Domain
• Isobutyryl-RYYRIK-NH_2, A Highly Potent Nociceptin Antagonist
• Conformation Change-sensing Assay Using Monoclonal Antibody for N-terminal Octapeptide Repreat Region of Prion Protein
• Structural Characterisitics of the N-Terminal Octapeptide Repeat Region of Prion Protein
• Structural Requirements of the N-terminal Octapeptide Repeat of Prion Protein
• Structural Requirement of the Acyl Group of Ac-RYYRIK-NH_2, an Antagonist of Algesic Neuropeptide Nociceptin
• Structure-Activity Studies on the Nociceptin Peptidic Antagonist Ac-RYYRIK-NH_2
• RESOLUTION OF AMINO ACIDS (XVI) : PREPARATION OF FOUR OPTICAL ISOMERS OF δ-HYDROXYLYSINE
• WALDEN INVERSION OF AMINOACIDS (VIII) : STEREOSPECIFIC SYNTHESES OF D-ISOSERINE AND D-ISOTHREONINE FROM L-SERINE AND L-THREONINE
• Lysine-49-Phospholipases A_2 from Trimeresurus flavoviridis Venom Are Membrane-Acting Enzymes
• BIOLOGICAL EVALUATION OF N-TERMINAL PENTA- AND OCTAPEPTIDES OF NEUROPEPTIDS γ, A HIGHLY POTENT TACHYKININ PEPTIDE
• Structural Characterization of Phe Residues in the p53 Tetramerization Domain
• RESOLUTION OF AMINO ACIDS (XVII) : EFFECTIVE ACYLS GROUPS ON THE HYDROLYSIS OF ACYLAMINO ACIDS BY MOLD AND HOG KIDNEY ACYLASES
• RESOLUTION OF AMINO ACIDS (XIII) : RESOLUTION OF α-FORMYL-ω-ACYL DERIVATIVES OF DL-LYSINE AND DL-ORNITHINE
• Receptor Binding Site for the Phe-2-Phenyl Group of Thrombin Receptor-Tethered Ligand Peptide : Analyses by Ala/Tyr Mutant Receptors
• Binding Properties of Chemical Substances to the Estrogen Receptor(PROCEEDINGS OF 24TH SYMPOSIUM ON TOXICOLOGY AND ENVIRONMENTAL HEALTH)
• 1^H-NMR STUDIES ON SPECIFIC INHIBITORY CONFORMATION OF DIPEPTIDES FOR SERINE PROTEASE (II) : CONFORMATION OF DIPEPTIDE CHYMOTRYPSIN INHIBITOR CONTAINING 2,3-METHANOPHENYLALANINE WITH THE (2S,3R)-CONFIGURATION
• Inactivation of Gramicidin S by Acylation of Two Ornithine Residues with Higher Fatty Acids
• Induced-fit Type Ligand Binding Guided by Free-rotatory Leu Residue Present in the 7th α-Helix Peptide in the Estrogen-related Receptor γ (ERRγ)
• Structural Studies of [2',6'-Dimethyl-L-tyrosine^1]Endomorphin-2 Analogues Containing Proline Mimics
• CONFORMATION OF AM-TOXIN IN SOLUTION
• RESOLUTION OF AMINO ACIDS (XIV) : RESOLUTION OF DL-2-AMINO-5-PHENYLPENTANOIC ACID HOMOLOGS
• SYNTHESIS OF DIKETOPIPERAZINE ANALOGS CONTAINING L-α-HYDROXY CARBOXYLIC ACID AND GLYCINE FOR APPLICATION TO ASYMMETRIC HYDROGENATION
• Contractile Activity of Drosophila FMRFamide-Related Peptides in the Meretrix Lusoria Heart Muscle
• Distinction of the binding modes for human nuclear receptor ERRγ between bisphenol A and 4-hydroxytamoxifen
• Drosophila Neuropeptide hugγ Present in the Clock Cells Important for Circadian Rhythm Oscillation
• Apis pdf gene expresses in circadian manner
• The Trp residue of opioid receptor TM5 present at the cell membrane interface is a molecular anchor for full activation
• Exploration of the Binding Site of ORL1 Nociceptin Receptor Antagonist
• Relationship between structure and P-glycoprotein inhibitory activity of dimeric opioid peptides containing the Dmt-Tic pharmacophore
• QCM-Analyses of the Intermolecular Interaction between Prion Protein N-Terminal Domains Having Increased Number of Octapeptide Repeat
• Functional Analysis of a Histidine Residue Essential for Receptor Activation of Delta Opioid Receptor
• Receptor Binding Characteristics of Tritium-Labeled Pure Antagonist Peptide for Hyperalgesic Nociceptin ORL1 Receptor
• Structural Analysis of Delta Opioid Receptor Dimer by Bivalent Deltorphin II Analogs
• Affinity Labeling of the ORL1 Nociceptin Receptor by Cys(Npys)-Elongated RYYRIK Peptide Antagonist
• Structural Essentials of Hyperalgesic Nociceptin ORL1 Receptor for Ligand Binding and Receptor Activation
• Structural Characteristics of Thr-Gly Dipeptide Repeat in the Drosophila Clock Protein PERIOD
• Processing of Precursor Protein of the Cricket Gryllus bimaclatus Circadian Rhythm Neuropeptide PDF and PAP and Their Axonal Transport
• Effects of the Halogenation of Phe-Phenyl Group of Two Consecutive Residues in Endomorphin-2 on the Interaction with the μ-Opioid Receptors
• The Effect of Halogenation of Phe-Phenyl Group of Two Consecutive Phe Residues Present in Neuropeptide Substance P on Its Specific Receptor Interaction
• Phosphatase assay for multi-phosphorylated substrates using phosphatase specific-motif antibody
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