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概要

• 論文の詳細を見る
• 2011-12-25

著者

• 下東 康幸

  Division Of Biology Faculty Of Science Fukuoka University

• Shimohigashi Yasuyuki

  九州大学 理学研究院化学部門構造機能生化学

• Shimohigashi Y

  Kyushu Univ. Fukuoka

• 下東 康幸

  九州大学大学院理学研究院

• Shimohigashi Yasuyuki

  Laboratory Of Structure-function Biochemistry Department Of Chemistry Faculty Of Sciences Kyushu Uni

• Shimohigashi Yasuyuki

  Laboratory Opf Biochemistry Department Of Chemistry Faculty Of Science Kyushu University

• Shimohigashi Yasuyuki

  Laboratory Of Structure-function Biochemistry Department Of Chemistry Faculty And Graduate School Of

• Shimohigashi Yasuyuki

  Laboratory Of Structure-function Biochemistry Department Of Molecular Chemistry Graduate School Of S

• Shimohigashi Y

  Laboratory Of Structure-function Biochemistry Faculty And Graduate School Of Science Kyushu Universi

• Shimohigashi Y

  Faculty And Graduate School Of Sciences Kyushu University

• Sasaki Yusuke

  Faculty And Graduate School Of Science Kyushu University

関連論文

• Splicing Variants of pdf Gene in the Honeybee Apis mellifera
• Gene Expression of Circadian Neuropeptide PDF in Honeybee
• Design and Synthesis of α-Helix Peptide Bonding to Prion Protein N-terminal Octarepeat Domain
• Immunological Evidences of Circadian Neuropeptide PDF Isoform Present at the Lamina Outer Cells and Varicose Network in the Optic Lobes of the Cricket Gryllus bimaculatus
• Identification of Novel Isofoms of the Circadian Neuropeptide PDF in the Silk Moth Bombyx mori and their Expression in Brain
• Triplicate Alternative Splicings that Produce Multiple Variants of the PERIOD Protein in the Silk Moth Bombyx mori by Deletion/Insertion of Peptides
• cDNA Cloning and mRNA Expression of the Circadian Neuropeptide PDF in the Silk Moth Bombyx mori
• Structural Analysis and Identification of Novel Isoforms of the Circadian Clock Gene period in the Silk Moth Bombyx mori(Neurobiology)
• Primary Structure Analyses of Circadian Neuropeptide PDF and Its Precursors in Insect Cicadae and Flies
• Two Distinctly Different Isoforms With/Without Pentapeptide Fragment in the Silk Moth Clock Protein PERIOD
• Synthesis of Endomorphin-2Analogues Containing Piperidinecarboxylic Acid (Pip) and 2-Azetidinecarboxylic Acid (Aze)
• Synthesis and Biological Activity of Endomorphin-2 Analogues Containing Pro Mimics
• Synthesis and Binding Activities of Endomorphin Analogs Containing 1-Aminocyclopropane-1-carboxylic Acid
• Synthesis and Receptor-Binding Activity of Morphiceptin Analogs Containing α, α-Disubstituted Glycine in the Position 2
• Synthesis and Receptor-binding Activity of Endomorphin Analogs Containing α, α-Disubstituted Glycine
• Molecular Cloning and In Situ Hybridization of Circadian Neuropeptide PDF Receptor in the Fruit Fly Drosophila melanogaster
• Structure-Activity Studies of FMRFamide-Related Peptides in Activating the Specific Receptor Present in the Housefly Musca domestica
• 昆虫の時計細胞がペプチドホルモンをつくる : 概日リズムを伝達するペースメーカーホルモン
• 昆虫の概日リズムペースメーカーペプチドホルモンPDF
• Ligand-inducing Conformation Changes in the Estrogen Receptor C-Terminal Tail Moiety and Their Sensing by Polyclonal Antibodies
• Structural Requirement of Housefly FMRFamide Peptides in Its Receptor Activation
• FMRFamide-Related Peptides in the Nervous System of the Housefly Musca domestica : cDNA Cloning and Actions on Clam Heart Contraction
• INTERACTION OF HIGHLY BIOACTIVE GRAMICIDIN S ANALOG LACKING HYDROPHILIC AMINO ACID RESIDUES WITH BIOMEMBRANES
• Double-labelled in situ Hybridization Reveals the Lack of Co-localization of mRNAs for the Circadian Neuropeptide PDF and FMRFamide in Brains of the Flies Musca domestica and Drosophila melanogaster
• IMMUNOCYTO- AND HISTOCHEMICAL ANALYSIS ON THE CIRCADIAN NEUROPEPTIDE PDF IN GRYLLUS BIMACULATUS(Physiology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
• Immunocytochemical Identification the Circadian Neuromodulator PDF in the Housefly Musca domestica : Formation of Mature Peptide
• Immunocytochemical Studies on the Circadian Neuropeptide PDF in the Cricket Gryllus bimaculatus
• Structural Characteristics of Drosophila Estrogen-related Receptor Ligand Binding Domain to Capture the Peptide and Non-peptide Ligands
• LOCALIZATION PROFILES OF ORCADIAN NEUROPEPTIDE PDF IN THE BRAIN OF FLIES, MUSCA DOMESTICA(Physiology,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
• cDNA Cloning and in situ Hybridization of Sulfated Peptide, Sulfakinin, on Housefly Musca domestica
• Functional Analysis of F-Domain Peptides Important for the Basal Constitutive Activity of Human Nuclear Receptor
• α-Helix Peptides for Bio-Panning in the Phage Display Method to Obtain the Antibodies Specific for Conformation Change in Nuclear Receptors
• Highly Sensitive Monoclonal Antibodies to Distinguish Conformational Changes Induced by Endocrine Disrupting Chemicals in the Estrogen Receptor
• Specific Affinity Labeling of Cys60 in the δ Opioid Receptor by Npys-containing Dynorphin A Analog
• Placenta Expressing the Greatest Quantity of Bisphenol A Receptor ERRγ among the Human Reproductive Tissues : Predominant Expression of Type-1 ERRγ Isoform
• 胎盤・胎児脳に高発現の自発活性化型核内受容体ERRγに対する環境ホルモン・ビスフェノールAの結合とリスク
• Direct Measure of Fluorescence Intensity for Efficient Receptor-binding Assay : Conjugates of Ethinylcarboxyestradiol and 5(and 6)-Carboxyfluorescein via α,ω-Diaminoalkanes as a Tracer for Estrogen Receptor
• The Conformation Change-Sensing Antibodies for Retinoid-Related Orphan Receptor Family
• Differential Receptor Recognition by Dmt-Containing Enkephalin Dimers Cross-Linked by Phenylenediamines
• The Molecular Mechanism of ORL1 Nociceptin Receptor in Activation : Residual Essentials in the Sixth Transmembrane Domain
• Structural Analysis of Excitatory Neuropeptides TEP-1 and TEP-2 Isolated from the Prosobranch Gastopod Thais clavigera
• Optimization of the N-Terminal Group of Ac-RYYRIK-NH_2 as ORL1 Receptor Antagonist
• The Effect of Amino Acid Substitution on Oligomerization of Octapeptide Repeat Structure in Prion Protein
• Structural Profiles for Coacervation of Elastin-derived Polypeptides
• The Output Mechanism of Circadian Pacemaker Neuropeptide PDF in the Regulation of Bimodal Locomotor Distribution
• Structural Evidence for Endocrine Disruptor Bisphenol A Binding to Human Nuclear Receptor ERRγ
• Immunological Confirmation of Circadian-Related Neuropeptide PDF-Isoform Peptide in the Cricket Gryllus bimaculatus
• Characterization and Application of Monoclonal Antibody Specific for Ser(P)-Gln Phosphorylation Motif
• Monoclonal Antibody Sensing Assay for Conformation Change Induced by Metal Binding to Prion Protein N-Terminal Octarepeat Domain
• Isobutyryl-RYYRIK-NH_2, A Highly Potent Nociceptin Antagonist
• Conformation Change-sensing Assay Using Monoclonal Antibody for N-terminal Octapeptide Repreat Region of Prion Protein
• Structural Characterisitics of the N-Terminal Octapeptide Repeat Region of Prion Protein
• Structural Requirements of the N-terminal Octapeptide Repeat of Prion Protein
• Structural Requirement of the Acyl Group of Ac-RYYRIK-NH_2, an Antagonist of Algesic Neuropeptide Nociceptin
• Multiple Post-Transcriptional Regulations in Circadian Pacemaker Neuropeptide pdf Gene
• Roles of Each Component of μ-Opioid Ligands Containing Dmt-Pyrazinones
• Synthesis and Bioactivity of Novel Type Pyrazinone Ring-Containing μ-Opioid Ligands
• Generation of a Selective Agonist for Mu-Opioid Receptors by the Dimerization of 2', 6'-Dimethyl-L-Tyrosine through Pyrazinone
• The Structure-Activity Relationship of Dmt-NH-X
• Synthesis of Pure Antagonist of ORL1 Nociceptin Receptor
• Residual Roles of Hydrophobic Amino Acids in the Fifth Transmembrane Domain of ORL1 Receptor in Its Activation
• Enkephalin Dimers Cross-Linked by Diaminobenzene for Homodimeric Opioid Receptors Expressed in COS-7 Cells
• Continuous Activation of the δ-Opioid Receptor by Affinity Labeling
• Lysine-49-Phospholipases A_2 from Trimeresurus flavoviridis Venom Are Membrane-Acting Enzymes
• BIOLOGICAL EVALUATION OF N-TERMINAL PENTA- AND OCTAPEPTIDES OF NEUROPEPTIDS γ, A HIGHLY POTENT TACHYKININ PEPTIDE
• Characteraization of Superstable Variant Peptide of Human p53 Tetramerization Domain
• Structural Characterization of Phe Residues in the p53 Tetramerization Domain
• Inactivation of Gramicidin S by Acylation of Two Ornithine Residues with Higher Fatty Acids
• Induced-fit Type Ligand Binding Guided by Free-rotatory Leu Residue Present in the 7th α-Helix Peptide in the Estrogen-related Receptor γ (ERRγ)
• Bisphenol A-Specific Nuclear Receptor ERRγ : Structure-Function Analysis of the Two Novel Isoforms Lacking Vital Peptide Fragment in the Ligand Binding Domain
• Molecular Recognition of Prion Protein via Its N-terminal Octapeptide Repeat Structure
• The Effects of Arg→Trp and Lys→Trp Substitutions for Arg-Lys^ Residues in a Superagonist [Arg-Lys^]-Nociceptin on the ORL1 Receptor Binding and Activation
• Molecular Mechanism of α-Helix Peptide That Inhibits Intermolecular Interaction of Prion Protein N-Terminal Tetrarepeat Domain
• Histidines as Structurally Essential Residue for the Delta Opioid Receptor Activation
• Structural Studies of [2',6'-Dimethyl-L-tyrosine^1]Endomorphin-2 Analogues Containing Proline Mimics
• Essential Amino Acid Residues in the ORL1 Receptor Transmembrane Domains for Receptor Activation
• Conformation Change of α-Helix Peptide for Sensing of Deactivation of Nuclear Receptor : Immunoassay Using Polyclonal Antibody Specific for the C-Terminal α-Helix 12 of Estrogen-Related Receptor γ(ERRγ)
• Hetero-Oligomer Formation of Peptides Derived from Tetramerization Domain in Tumor Suppressor Protein p53
• Specific Dimerization of Prion Protein N-terminal Domain
• Distinction of the binding modes for human nuclear receptor ERRγ between bisphenol A and 4-hydroxytamoxifen
• Conformation Sensing Assay Using Polyclonal Antibody Specific for the C-terminal α-helix of Glucocorticoid Receptor and Progesterone Receptor
• Bioactive Conformation of a D-Trp-Containing Cardioexcitatory Tripeptide Isolated from the Sea Hare Aplysia
• Drosophila Neuropeptide hugγ Present in the Clock Cells Important for Circadian Rhythm Oscillation
• Apis pdf gene expresses in circadian manner
• The Trp residue of opioid receptor TM5 present at the cell membrane interface is a molecular anchor for full activation
• Exploration of the Binding Site of ORL1 Nociceptin Receptor Antagonist
• Relationship between structure and P-glycoprotein inhibitory activity of dimeric opioid peptides containing the Dmt-Tic pharmacophore
• QCM-Analyses of the Intermolecular Interaction between Prion Protein N-Terminal Domains Having Increased Number of Octapeptide Repeat
• 環境化学物質の内分泌撹乱作用, そして実験の撹乱
• Functional Analysis of a Histidine Residue Essential for Receptor Activation of Delta Opioid Receptor
• Receptor Binding Characteristics of Tritium-Labeled Pure Antagonist Peptide for Hyperalgesic Nociceptin ORL1 Receptor
• Structural Analysis of Delta Opioid Receptor Dimer by Bivalent Deltorphin II Analogs
• Affinity Labeling of the ORL1 Nociceptin Receptor by Cys(Npys)-Elongated RYYRIK Peptide Antagonist
• Structural Essentials of Hyperalgesic Nociceptin ORL1 Receptor for Ligand Binding and Receptor Activation
• Structural Characteristics of Thr-Gly Dipeptide Repeat in the Drosophila Clock Protein PERIOD
• Processing of Precursor Protein of the Cricket Gryllus bimaclatus Circadian Rhythm Neuropeptide PDF and PAP and Their Axonal Transport
• Effects of the Halogenation of Phe-Phenyl Group of Two Consecutive Residues in Endomorphin-2 on the Interaction with the μ-Opioid Receptors
• The Effect of Halogenation of Phe-Phenyl Group of Two Consecutive Phe Residues Present in Neuropeptide Substance P on Its Specific Receptor Interaction
• Phosphatase assay for multi-phosphorylated substrates using phosphatase specific-motif antibody
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