INFLUENCES OF ALKALINE IONIZED WATER ON MILK YIELD, BODY WEIGHT OF OFFSPRING AND PERINATAL DAM IN RATS

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概要

• 論文の詳細を見る

• The authors previously reported that male offspring of mother rats given alkaline ionized water (AKW) showed a significantly higher body weight by day 14 after birth than did offspring of mother rats given tap water (TPQ) ; furthermore, marked myocardial necrosis and fibrosis were observed particularly in the former male offspring at the age of 15 weeks. In the present experiment we looked for differences in bioparameters, namely the milk yeild of mothers and suckled milk volume of the offspring, between the AKW-and the TPW-treated groups in order to reveal the factors which cause the unusual body weight gain in the offspring. Even though we were able to repeat our previous observation (the body weight of the male offspring of the AKW group increased significantly more by day 14 and 20 after birth and of the female by day 20 after birth than did that of the TPW group (p<0.05), no significant difference was noted in any of the bioparameters, including those related to milk production and consumption. It is thus suspected that the water-hydrated cation, which was transferred either to the fetus through the placenta or to the offspring through the milk, might be the cause of the unusual body weight increase. Since calcium plays an important role in skeletal formation, it is tentatively concluded tht the higher calcium concentration of AKW enriched the mother, serum calcium which was transferred to the fetus through the placenta and to the offspring through the milk.

• 日本トキシコロジー学会の論文

著者

• WATANABE Toshi

  Department of Veterinary Biochemistry, College of Bioresource Sciences, Nihon University

• Watanabe Toshi

  Departments Of Veterinary Biochemistry College Of Bioresource Sciences Nihon University

• Kamata Hiroshi

  Nihon Univ. School Of Veterinary Medicine Kanagawa

• 渡辺 稔之

  Medicinal Safety Research Laboratories Sankyo Co. Ltd.

• Fukuda Y

  Departments Of Veterinary Microbiology College Of Bioresource Sciences Nihon University

• UWATOKO Kazuhiro

  Departments of Veterinary Epizootiology, College of Bioresource Sciences, Nihon University

• PAN In-Jen

  Veterinary Clinical Pathology, College of Bioresource Science, Nihon University

• MURASUGI Eiji

  Second Veterinary Internal Medicine, College of Bioresource Science, Nihon University

• KAMATA Hiroshi

  Veterinary Microbiology, College of Bioresource Sciences, Nihon University

• UWATOKO Kazuhiro

  Veterinary Virology, College of Bioresource, Nihon University

• Pan In-jen

  Departments Of Veterinary Epizootiology College Of Bioresource Sciences Nihon University

• Murasugi Eiji

  Departments Of Second Veterinary Internal Medicine And Veterinary Pathology College Of Bioresource S

• Kamata H

  Departments Of Veterinary Microbiology College Of Bioresource Sciences Nihon University

• FUKUDA Youichi

  Veterinary Microbiology, College of Bioresource Sciences, Nihon University

• Uwatoko Kazuhiro

  Departments Of Veterinary Epizootiology College Of Bioresource Sciences Nihon University

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