Effect of Heparin on Hemagglutination by Equine Arteritis Virus.
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概要
- 論文の詳細を見る
Heparin inhibited hemagglutination (HA) by equine arteritis virus (EAV) as well as did HA by Aujeszky's disease virus (ADV), but failed to inhibit HA by parainfluenza virus type 3 (PIV-3). The minimal concentration of heparin required to inhibit 8 HA U of EAV was 0.1 U/ml. In addition, most EAV hemagglutinin was retained by heparin acrylic beads, as was ADV hemagglutinin, but was not PIV-3 hemagglutinin. Mouse erythrocytes failed to combine with the HA inhibitory factor of heparin. However, mouse erythrocytes treated with heparinase had greatly reduced agglutinability by EAV. All these findings suggest that a heparin-like molecule on the surface of mouse erythrocytes serves as the virus-cell receptor.
- 公益社団法人 日本獣医学会の論文
著者
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Fukunaga Yoshio
Epizootic Research Station Equine Research Institute
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Pan In-jen
Departments Of Veterinary Epizootiology College Of Bioresource Sciences Nihon University
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AKASHI Hiroomi
National Institute of Animal Health
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Inaba Yuji
Department Of Pediatrics Mizonokuchi Hospital Teikyo University School Of Medicine
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Kubota Tomohiro
Department Of Pediatrics Kagoshima University Graduate School Of Medical And Dental Sciences
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Sano Yoshitaka
Department of Appilied Biology, Faculty of Textile Science, Kyoto Institute of Technology
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UWATOKO Kazuhiro
Department of Veterinary Epizootiology, College of Bioresource Sciences, Nihon University
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FUKUNAGA Yoshio
Epizootic Research Station, Equine Research Institute, The Japan Racing Association
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ASAGOE Tetsuo
Department of Veterinary Epizootiology, College of Bioresource Sciences, Nihon University
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KANAYA Jyunichi
Department of Veterinary Epizootiology, College of Bioresource Sciences, Nihon University
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INABA Yuji
Department of Veterinary Epizootiology, College of Bioresource Sciences, Nihon University
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PAN In-Jen
Department of Veterinary Epizootiology, College of Bioresource Sciences, Nihon University
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