PLASMA ASPARTATE LEVELS IN RATS FOLLOWING ADMINISTRATION OF MONOPOTASSIUM ASPARTATE VIA THREE ROUTES
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概要
- 論文の詳細を見る
Plasma aspartate levels were measured after potassium aspartate administration through different routes to rats of various ages. The changes in plasma levels were most significant with intraperitoneal injection. Dose- and age-related responses to aspartate load were obtained. The present data suggest that a marked elevation of plasma aspartate levels may result in neuronal necrosis. By comparing the plasma aspartate levels with the results on hypothalamic lesion (Okaniwa et al., 1979), plasma peak value associaed with the lesion was estimated in each case of various administration routes and rat ages.
- 日本トキシコロジー学会の論文
- 1979-11-15
著者
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Kishi Tetsuya
Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.
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Iwasawa Yasuo
Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.
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Chibata Ichiro
Research Laboratories Tanabe Seiyaku Co. Ltd.
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Chibata Ichiro
Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.
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ITOH Hiroshi
Research Institute of Instrumentation Frontier, National Institute of Advanced Industrial Science an
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Kawashima Keisuke
Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.
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Itoh Hiroshi
Research & Development Center Nosan Corporation
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Itoh Hiroshi
Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.
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