M. V. I. (Multi-Vitamin Infusion)配合時の輸液中における抗生物質の力価変化およびビタミンの安定性

概要

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The antibacterial activity of antibiotics and the stability of vitamins in 8 transfusions mixed with antibiotics and multi-vitamin in fusion (M. V. I.) were investigated and the following results were obtained. No change in appearance was observed 24 hr after the combination of antibiotics and M. V. 1. pH was changed only when antibiotics and M. V. 1. were mixed in 5% Klinit. When mitomycin C was mixed in EL #3, Paremental A, Paremental B, Hicaliq #1 or Hicaliq #2, the lowering of antibacterial activity of mitomycin C was observed regardless of the presence of M. V. 1. Vitamin A in Moriamin SN or Hicaliq #1 was decomposed by light. Vitamin B_1 was decomposed with amino acid products such as Proteamin 12X and Moriamin SN, but this decomposition was decreased in the presence of rolitetracycline. Vitamin B_3 and Vitamin C were stable in the presence of transfusions and antibiotics.
日本医療薬学会の論文
1984-12-20