乳糖分解酵素製剤の品質比較 (3) : 分包製品について

概要

論文の詳細を見る
Five lactase preparations in powder (G-TT, O-ON, L-WM, L-NK, ORG) were compared in terms of sensory test, weight deviation, potency deviation and residual rate. Further, the changes in appearance and potencies were examined for the maximum of 26 weeks in three conditions : A (5°±1°, RH 40-50%), B (23°±1°, RH 75-80%) and C (40°±1°, RH 90-92%). Consequently G-TT showed the poorest result in the sensory test, while O-ON recorded a high residual rate and it was found that the actual dose of this agent was smaller than that was expected. L-WM was recognized as the best product in the test of change with time, but about 10% of L-WM was deteriorated at the part of cutting. ORG showed faster change in appearance than any other product due to poor moisture proofing. L-NK proved not inferior in any test.
日本医療薬学会の論文
1982-06-20