Psychoneuroimmunology(心身医学の基礎研究)(第31回日本心身医学会総会)

概要

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Cytokines released from activated T lymphocytes effect not only immune circuit but also the nervous system. Neurotransmitters or neuropeptides released after nervous stimulation transmit signals to the nerve system as well as to the immune system. Therefore, bidirectional signal interactions are found to be acrossed between the nervous and immune systems. Various reports have been accumulated the facts that different forms of stress influence immune regulation either up or down in immune response. In general, the immune response is known to be decreased after various forms of stress applited to mice, and the altered immune response was returned to the normal level by the exposure to aromatic fragrances in the stressed-mice. Furthermore, the alteration of the immune response was not able to recover by the pretreatment of the stressed mice with procain before the exposure to the fragrance. The results indicate that the sensory system of the body may regulate immune function, and the effect of the fragrance on the stressed mice with decreased immune response was proved to be recovered via the olfactory system. Further sudies on the effects of the olfactory system by a variety of fragrance which reflect to immune responses together with other sensory systems are expected to be carried out.
日本心身医学会の論文
1991-01-08