<原著論文>脳磁図を用いた頚椎症性脊髄症の客観的治療効果判定法に関する研究

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Our aim in this study was to establish an objective quantitation of thesurgical effects for cervical spondylotic myelopathy with the aid of an advanced helmetshaped,whole-head magnetoencephalography system. In eight surgical cases of cervicalspondylotic myelopathy, we measured the pre- and postoperative magneticresponses to somatosensory stimuli, with particular emphasis on the first (1M) andsecond (2M) peaks. Both the peak latency and dipole intensity of 1M and 2M improvedsix months after surgery. The recovery of the dipole intensity was particularlysatisfactory, recovering to where there was no significant difference in comparison withnormal controls.In case 5, although the preoperative 1M peaks of SEFs with median nerve stimuliwere not identified, they did appear one month after surgery. The 2M peaks of hisSEFs, with a shortened peak latency and an increased dipole intensity, were clearlyidentified during this study. The results of 2M peak analyses of this patient correlatedwell with postoperative neurological improvement. Our results suggest that pre- andpostoperative sequential analyses of 1M and 2M peaks may provide the criteria forcurative surgical effects and prognosis prediction factors of cervical spondyloticmyelopathy.
秋田大学の論文