Synthesis of Hydroxyethyl-type Inhibitor Containing Superior BACE1 Cleavage Sequence
スポンサーリンク
概要
- 論文の詳細を見る
- 2013-03-01
著者
-
AKIYAMA Tomomi
Department of Veterinary Pathology, Tottori University
-
Konno Hiroyuki
Graduate School Of Medical Science Kyoto Prefectural University Of Medicine
-
Yamaguchi Makoto
Department of Architecture, Faculty of Engineering, Nippon Bunri University, Japan.
-
Kobayashi Kazuya
Department Of Biological Sciences And Informatics Keio University
-
Akaji Kenichi
Department Of Chemistry Graduate School Of Medical Science Kyoto Prefectural University Of Medicine
-
Hattori Yasunao
Department Of Chemistry Graduate School Of Medicinal Science Kyoto Prefectural University Of Medicin
-
Teruya Kenta
Department Of Medicinal Chemistry Graduate School Of Medical Science Kyoto Prefectural University Of
-
GOTO Saki
Department of Medicinal Chemistry, Kyoto Pharmaceutical University
-
SOHMA Yohei
Department of Medicinal Chemistry, Kyoto Pharmaceutical University
-
YAMAGUCHI Makoto
Department of Medicinal Chemistry, Kyoto Pharmaceutical University
関連論文
- Effect of Multimerization of a Linear Arg-Gly-Asp Peptide on Integrin Binding Affinity and Specificity
- The Dugesia ryukyuensis Database as a Molecular Resource for Studying Switching of the Reproductive System
- Lymphoepithelial Thymoma Characterized by Proliferation of Spindle Cells in a Samoyed Dog
- Blast Resistance of Polyethylene Fiber Reinforced Concrete to Contact Detonation
- Synthesis and Activity of a New Type of Anti-HIV Agents, Conjugate of HIV Protease Inhibitor with Reverse Transcriptase Inhibitor
- Synthesis of an HIV-1 Protease Analogue by the Chemoselective Ligation Method Using a New Disulfide Type Linker
- CHARACTERIZATION OF PIGMENT COMPONENT IN THE PLANARIAN DUGESIA RYUKYUENSIS(Biochemistry,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
- ELECTRON MICROSCOPIC STUDIES ON EYE-REGION OF "MENASHI MUTANT" IN THE PLANARIAN DUGESIA RYUKUENSIS(Cell Biology and Morphology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
- STUDY ON ENDOCRINE-RELATED MOLECULES IN PLANARIAN(Endocrinology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
- A CONCISE SYNTHESIS OF SOLAMIN AND CIS-SOLAMIN, MONO-THF ACETOGENINS FROM ANNONA MURICATA
- P-364 Total Synthesis of Murisolin, Murisolin A, and 16,19-cis-Murisolin
- Small-sized HIV Protease Inhibitors Containing Allophenylnorstatine as a Substrate Transition-state Mimic
- Design of HIV Protease Inhibitors Based on the Transition State Analogue Concept
- Electrostatic control of particle deposition
- Synthesis and Structure Activity Relationship Studies of Miraziridine A, a Cysteine Protease Inhibitor
- Evaluation of Peptide-Based Inhibitors using R188I Mutant of SARS 3CL Protease as a Proteolysis-Resistant Mutant
- Synthetic Studies on Miraziridine A, a Cysteine Protease Inhibitor Isolated from Theonella aff. mirabilis
- P-61 SYNTHESES OF TOKARAMIDE A AND MIRAZIRIDINE A CYSTEINE PROTEASE INHIBITORS FROM THEONELLA AFF. MIRABILIS
- Synthetic Studies of Tokaramide A and Miraziridine A Isolated from Marine Sponge Theonella aff. mirabilis
- Molecular Cloning and Analysis of the 5'-Flanking Region of the Human Thiamin Pyrophosphokinase Gene
- Neoblast-enriched fraction rescues eye formation in eye-defective planarian 'menashi' Dugesia ryukyuensis
- MAKING ASEXUALS SEXUAL IN THE PLANARIAN, DUGESIA RYUKYUENSIS
- Switching from Asexual to Sexual Reproduction in the Planarian Dugesia ryukyuensis : Bioassay System and Basic Description of Sexualizing Process(Reproductive Biology)
- Synthesis of HIV Protease Dipeptide Inhibitors and Prodrugs
- Studies on Structure-Activity Relationship of HTLV-1 Protease Inhibitors
- Total Synthesis of Human T-cell Leukemia Virus Type-1 Protease via the Thioester Method
- Synthesis of Phosphorylated Polypeptide Using an Expressed Peptide as a Building Block
- Use of an Expressed Peptide Segment as a Building Block for the Preparation of Phosphorylated Polypeptide via the Thioester Method
- Evaluation of Susceptibility to Hydrogen Embrittlement of 7075 Aluminum Alloy by Hydrogen Addition Using Flax-Treatment Method
- WIENER-HOPF ANALYSIS OF THE PLANE WAVE DIFFRACTION BY A SEMI-INFINITE PARALLEL-PLATE WAVEGUIDE WITH FIVE DIFFERENT MATERIAL LOADING : REVISITED
- RADAR CROSS SECTION OF A FINITE PARALLEL-PLATE WAVEGUIDE WITH THREE-LAYER MATERIAL LOADING : THE CASE OF H POLARIZATION
- WIENER-HOPF ANALYSIS OF THE VECTOR DIFFRACTION PROBLEM FOR A CIRCULAR WAVEGUIDE CAVITY
- WIENER-HOPF ANALYSIS OF THE VECTOR DIFFRACTION PROBLEM FOR A CIRCULAR WAVEGUIDE CAVITY
- Plane Wave Diffraction by a Thin Material Strip : Solution by the Analytical-Numerical Approach
- Plane Wave Diffraction by a Thin Material Strip : Solution by the Wiener-Hopf Technique
- C-1-38 Plane Wave Diffraction by a Thin Material Strip : Solution by the Analytical-Numerical Approach
- C-1-37 Plane Wave Diffraction by a Thin Material Strip : Solution by the Wiener-Hopf Technique
- Amyloid Beta42 Fibril Mimic Peptides Inhibit the Amyloid Beta42 Fibrillation by Binding to the Prefibrillar Soluble Oligomers
- C-1-36 Wiener-Hopf Analysis of the Axial Symmetric Diffraction Problem for a Circular Waveguide Cavity
- Wiener-Hopf Analysis of the H-Polarized Diffraction by a Strip in the Plane Interface between Two Semi-Infinite Media : Comparison of Two Asymptotic Solutions
- Wiener-Hopf Analysis of the E-Polarized Diffraction by a Strip in the Plane Interface between Two Semi-Infinite Media : Comparison of Two Asymptotic Solutions
- Wiener-Hopf Analysis of the E-polarized Diffraction by a Strip in the Plane Interface between Two Semi-Infinite Media : Comparison of Two Asymptotic Solutions
- Studies on N^〈in〉-Protecting Groups during the Synthesis of Trp : Containing Cystine Peptide by Silyl Chloride Sulfoxide Method
- A Reductive Acidolysis Final Deprotection Strategy in Solid Phase Peptide Synthesis Based on Safety-Catch Protection
- Localization of mitochondrial ribosomal RNA on the chromatoid bodies of marine planarian polyclad embryos
- Syntheses and Evaluations of Peptide-Based Inhibitors Using R188I Mutant of SARS 3CL Protease
- Synthetic Studies on Callipeltins B and E Isolated from Marine Sponge
- Synthesis of Human C-Type Natriuretic Peptide 22 Using Chlorotrityl Resin and Tetrafluoroboric Acid Deprotection
- SYNTHESES AND STRUCTURE-ACTIVITIES RELATIONSHIPS OF SMALLSIZED ATRIAL NATRIURETIC PEPTIDE (ANP) DERIVATIVES WITH POTENT ACTIVITY
- SYNTHESES AND STRUCTURE-ACTIVITY RELATIONSHIPS OF SMALL-SIZED ATRIAL NATRIURETIC PEPTIDE (ANP) DERIVATIVES
- Solid Phase Synthesis of a Mercaptoamide Peptide Using New Linkers
- SYNTHESES OF CYSTINE-PEPTIDES BY A NEW DISULPHIDE BOND FORMING REACTION
- AROUND THE NAGATA'S METRICS
- SYNTHESES AND BIOLOGICAL ACTIVITIES OF SEVERAL NEWLY ISOLATED NATRIURETIC PEPTIDES
- The Development of a Japanese Version of the Short-Form McGill Pain Questionnaire
- Endogenous tenascin-C enhances glioblastoma invasion with reactive change of surrounding brain tissue
- Synthetic study of callipeltin A, an anti-HIV cyclic depsipeptide isolated from marine sponge
- Wiener-Hopf Analysis of the H-polarized Plane Wave Diffraction by a Thin Material Strip
- Synthesis of Annonacin Isolated from Annona densicoma
- Design of BACE1 Inhibitors Containing 5-Nitro-Isophthalamide
- Structure Activity Relationship Study of SARS Coronavirus 3CL Protease Inhibitors with an Electrophilic Aryl Ketone Structure
- Development of Stimulus Responsive Thiol Releasing System for Controlling Activity of Cysteine Protease
- Synthesis and Evaluation of Small Peptide Inhibitors for SARS 3CL Protease
- A Semi-synthetic Route for Mouse Prion Protein Chemically Modified at the C-terminal
- Transfinite large inductive dimensions modulo absolute Borel classes
- The behaviour of dimension functions on unions of closed subsets
- Diffraction by a Semi-Infinite Parallel-Plate Waveguide with Five Different Material Loading : The Case of E Polarization
- Diffraction by a Semi-Infinite Parallel-Plate Waveguide with Five Different Material Loading : The Case of H Polarization
- Evaluation of modified proteins for targeting exogenously prepared proteins on the cell surface
- Evaluation of Substrate Specificities for BACE1 using Synthetic Peptide Libraries
- Estimations of small transfinite dimension in separable metrizable spaces
- HIGH-FREQUENCY DIFFRACTION BY A STRIP LOCATED ON AN INFINITE MATERIAL SLAB
- Convergent Synthesis of Dolastatin 15 by Solid Phase Coupling of N-methylamino Acid
- Total Synthesis of (-)-Mirabazole B Using a Chloroimidazolidium Reagent, CIP
- Efficient Synthesis of Alamethicin using a Newly Developed Coupling Reagent, CIP
- Efficient Coupling of Dialky Amino Acid Using a Chloro Imidazolidium Reagent, CIP
- On Generalized Gamma Functions Occurring in Diffraction Theory
- On the Factorization of Certain Kernels Arising in Functional Equations of the Wiener-Hopf Type
- 1F1524 P73 膵導管細胞HCO_3^-分泌システムの数理モデル(数理生物学1,第49回日本生物物理学会年会)
- Design, Synthesis and Evalution of Tripeptidomimetics with Arylketone as Inhibitors of SARS-CoV 3CL Protease
- Synthesis of Cyclic Lipopeptide Derivatives of Burkholdines and Its Antifungal Activity
- Synthetic Study of the Depsipeptides Analogues of Callipeltin B and Its Cytotoxicity
- Evaluation of Inhibitory Activities of Curcumin Derivatives Using BACE1 and Amyloid Beta Peptide
- Synthesis of O-Acyl Isopeptide by Use of Native Chemical Ligation to Efficiently Construct Hydrophobic Polypeptide
- Selective Liposome Binding of Protein Modified with Hydrophobic Compounds at the C-Terminal
- Fano-Resonance Gain by Dephasing Electron--Hole Cooper Pairs in Semiconductors
- Detection of a large heterozygous deletion and a splicing defect in the CFTR transcripts from nasal swab of a Japanese case of cystic fibrosis
- Terumo-Triplex grafts for total arch replacement : analysis of postoperative graft performance
- Optical Compensation Method for In-plane Switching Twisted Nematic Mode
- Viewing Angle Characteristics and Cell Gap Tolerance of the In-plane Switching Twisted Nematic Mode
- Amorphous In-Plane Switching Twisted Nematic Liquid Crystal Displays Fabricated without Rubbing Process Show a Wide Viewing Angle and Fast Response Characteristics
- Electro-Optical Properties of the In-Plane Switching Twisted Nematic Mode
- Solutions of Wave Scattering Problems for a Class of the Modified Wiener-Hopf Geometries
- Evaluation of a tooth bleaching system incorporating titanium dioxide : Influence of the concentrations of hydrogen peroxide and titanium dioxide on bleaching effect
- Plane Wave Diffraction by a Strip: Exact and Asymptotic Solutions
- Synthesis of Hydroxyethyl-type Inhibitor Containing Superior BACE1 Cleavage Sequence
- Structural Analysis of SARS 3CL Protease Complexed with Peptide-Mimetic Inhibitors
- Synthesis and Evaluation of Serine Derivatives for SARS 3CL protease