Increasing Effect of an Oral Intake of L-Hydroxyproline on the Soluble Collagen Content of Skin and Collagen Fragments in Rat Serum
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概要
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We examined the effects of oral L-hydroxyproline (Hyp) on collagen in the body. After 2 weeks' administration of Hyp (0.5 or 1 g/kg) to F344 male rats, the soluble collagen content of the skin had increased, and the serum concentration of collagen peptides was correlated with the skin content of soluble collagen. This result suggests that oral Hyp augmented collagen metabolism.
- 2012-06-23
著者
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Morishita Koji
Healthcare Product Development Center Kyowa Hakko Bio Co. Ltd.
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Morishita Koji
Healthcare Products Development Center Kyowa Hakko Bio Co. Ltd.
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Yamasaki Motoo
Tokyo Research Laboratories Kyowa Hakko Kogyo Co. Ltd
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Takao Toshifumi
Laboratory Of Protein Profiling And Functional Proteomics Institute For Protein Research Osaka Unive
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Suto Kouzou
Laboratory Of Protein Profiling And Functional Proteomics Institute For Protein Research Osaka University
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AOKI Mami
Healthcare Products Development Center, KYOWA HAKKO BIO CO., LTD.
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KOMATSU Miho
Healthcare Products Development Center, KYOWA HAKKO BIO CO., LTD.
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KAMIMURA Ayako
Healthcare Products Development Center, KYOWA HAKKO BIO CO., LTD.
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Komatsu Miho
Healthcare Products Development Center Kyowa Hakko Bio Co. Ltd.
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Aoki Mami
Healthcare Products Development Center Kyowa Hakko Bio Co. Ltd.
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Kamimura Ayako
Healthcare Products Development Center Kyowa Hakko Bio Co. Ltd.
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Yamasaki Motoo
Tokyo Research Park Kyowa Hakko Kirin Co. Ltd.
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