Effect of preparation route on the degradation behavior and ion releasability of siloxane-poly(lactic acid)-vaterite hybrid nonwoven fabrics for guided bone regeneration
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概要
- 論文の詳細を見る
Two types of nonwoven fabric, consisting of siloxane-doped vaterite (SiV) and poly(lactic acid) (PLA), for guided bone regeneration (GBR) were prepared by an electrospinning. One of the fabrics, SiV-PLA(M), was derived from PLA mixed with the solution of SiV dispersed in chloroform. Another one, SiV-PLA(K), was derived from a composite prepared by kneading SiV and PLA while heating at 200°C. The SiV-PLA(K) fabric shows higher degradability in dilute NaOH aq. than the SiV-PLA(M) fabric. To improve the cellular compatibility of the fabric, the fibers were coated with hydroxyapatite (HA) by soaking in simulated body fluid. The HA-coated SiV-PLA(K) fabric showed the release of silicate ions; the amount was reduced by 1/5 to 1/8 compared with that of the HA-coated SiV-PLA(M) fabric, and the excessive release was controlled. The preparation route of kneading at 200°C led to formation of a fabric with degradation behavior and ion releasability effective for bone regeneration.
- 日本歯科理工学会の論文
- 2011-03-01
著者
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Nakamura Jin
Department Of Applied Physics And Chemistry The University Of Electro-communications
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Ban Seiji
Department Of Biomaterials Science Graduate School Of Medical And Dental Sciences Kagoshima Universi
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OTA Yoshio
Yabashi Industries Co. Ltd.
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Obata Akiko
Dep. Of Frontier Materials Graduate School Of Engineering Nagoya Inst. Of Technol.
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Obata Akiko
Department Of Frontier Materials Graduate School Of Engineering Nagoya Institute Of Technology
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Kasuga Toshihiro
Nagoya Inst. Of Technol. Dep. Of Frontier Materials Gokiso
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Kasuga Toshihiro
Department Of Frontier Materials Graduate School Of Engineering Nagoya Institute Of Technology
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Kasuga Toshihiro
Department Of Astronomical Science School Of Physical Science The Graduate University For Advanced S
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Wakita Takashi
Department Of Frontier Materials Graduate School Of Engineering Nagoya Institute Of Technology
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Ban Seiji
Department Of Biomaterials Science Field Of Oral And Maxillofacial Rehabilitation Course For Advance
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Nakamura Jin
Department Of Frontier Materials Graduate School Of Engineering Nagoya Institute Of Technology
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OTA Yoshio
Yabashi Industries Co., Ltd.
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