Preparation of siloxane-containing vaterite/poly (L-lactic acid) hybrid microbeads with silicate and calcium ions-releasing ability
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概要
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Siloxane-containing vaterite (SiV)/poly (L-lactic acid) (PLLA) hybrids have the releasing-ability of silicate and calcium ions for gene-activation. In the present paper a new types of beads were prepared using the hybrids via an electrospraying method. The diameters of the beads were controlled in the range of ∼65 to ∼180 µm by increasing the feeding rate from 0.1 to 0.9 ml/min. Depressed areas could be observed on the surface of the beads. The SiV particles with concentration of 10 and 20 wt % in the beads were completely enclosed by the PLLA matrix. These beads showed the controlled release of silicate and calcium ions in Tris buffer solution.
著者
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Nakamura Jin
Department Of Applied Physics And Chemistry The University Of Electro-communications
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OBATA Akiko
Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine
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KASUGA Toshihiro
Department of Materials Science and Engineering, Nagoya Institute of Technology
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Obata Akiko
Dep. Of Frontier Materials Graduate School Of Engineering Nagoya Inst. Of Technol.
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Obata Akiko
Department Of Frontier Materials Graduate School Of Engineering Nagoya Institute Of Technology
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Poologasundarampillai Gowsihan
Department of Frontier Materials, Graduate School of Engineering, Nagoya Institute of Technology
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Kasuga Toshihiro
Department Of Astronomical Science School Of Physical Science The Graduate University For Advanced S
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Nakamura Jin
Department Of Frontier Materials Graduate School Of Engineering Nagoya Institute Of Technology
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