Assessment of Prion Inactivation by Fenton Reaction Using Protein Misfolding Cyclic Amplification and Bioassay
スポンサーリンク
概要
- 論文の詳細を見る
An abnormal isoform of the prion protein, associated with transmissible spongiform encephalopathies, retains infectivity even after undergoing routine sterilization processes. We found that a formulation of iron ions combined with hydrogen peroxide effectively reduced infectivity and the level of abnormal isoforms of the prion protein in scrapie-infected brain homogenates. Therefore, the Fenton reaction has potential for prion decontamination.
- 社団法人 日本農芸化学会の論文
- 2007-08-23
著者
-
Akagawa Mitsugu
Department of Biological Chemistry, Division of Applied Life Science, Graduate School of Life and En
-
Yoshioka Miyako
Prion Disease Research Center, National Institute of Animal Health
-
Murayama Yuichi
Prion Disease Research Center, National Institute of Animal Health
-
TAKATA Masuhiro
Prion Disease Research Center, National Institute of Animal Health
-
YOKOYAMA Takashi
Prion Disease Research Center, National Institute of Animal Health
-
MOHRI Shirou
Prion Disease Research Center, National Institute of Animal Health
-
Takata Masuhiro
Prion Disease Research Center National Institute Of Animal Health
-
Mohri Shirou
National Inst. Animal Health Ibaraki Jpn
-
Mohri Shirou
National Inst. Animal Health Ibaraki
-
Mohri Shirou
Prion Disease Research Center National Institute Of Animal Health
-
Akagawa Mitsugu
Department Of Applied Bioorganic Chemistry Division Of Life Science Graduate School Of Agricultural
-
Suyama Kyozo
Sports Nutrition Department Sendai University
-
HORII Hiroko
Prion Disease Research Center, National Institute of Animal Health
-
Akagawa Mitsugu
Department Of Biological Chemistry Division Of Applied Life Science Graduate School Of Life And Envi
-
Akagawa Mitsugu
Department Of Biological Chemistry Division Of Applied Life Science Graduate School Of Life And Envi
-
Yoshioka Miyako
Prion Disease Research Center National Institute Of Animal Health
-
Horii Hiroko
Prion Disease Research Center National Institute Of Animal Health
-
Yokoyama Takashi
Prion Disease Research Center National Institute Of Animal Health
-
Takata Masuhiro
Prion Disease Res. Center National Inst. Of Animal Health
関連論文
- Pro-Oxidant Action of Pyrroloquinoline Quinone: Characterization of Protein Oxidative Modifications
- Examination of the Offspring of a Japanese Cow Affected with L-Type Bovine Spongiform Encephalopathy
- Immunohistochemical Detection of Disease-Associated Prion Protein in the Intestine of Cattle Naturally Affected with Bovine Spongiform Encephalopathy by Using an Alkaline-Based Chemical Antigen Retrieval Method
- スクレイピープリオン蛋白質(PrP27-30)の構造変化と,プロテイナーゼK抵抗性およびプリオン感染性の関連(ウイルス学)
- Assessment of Prion Inactivation by Combined Use of Bacillus-Derived Protease and SDS
- 小沢義博氏「アメリカのBSE対策の現状」に述べられた21ヵ月齢牛の判定に関するコメントに対する反論
- Human Serum Albumin as an Antioxidant in the Oxidation of (−)-Epigallocatechin Gallate: Participation of Reversible Covalent Binding for Interaction and Stabilization
- Rapid PrP^ Detection in Lymphoid Tissue and Application to Scrapie Surveillance of Fallen Stock in Japan : Variable PrP^ Accumulation in Palatal Tonsil in Natural Scrapie
- 組織の変敗が牛海綿状脳症の診断エライザ法に及ぼす影響(ウイルス学)
- Characterization and Application of a Novel RNA Aptamer against the Mouse Prion Protein
- Covalent Binding of Tea Catechins to Protein Thiols: The Relationship between Stability and Electrophilic Reactivity
- Applicability of Current Bovine Spongiform Encephalopathy (BSE) Diagnostic Procedures for Chronic Wasting Disease (CWD)
- Western blot assessment of prion inactivation by alkali treatment in the process of horticultural fertilizer production from meat meal(Fertilizers and Soil Amendments)
- Fusion of Doppel to Octapeptide Repeat and N-Terminal Half of Hydrophobic Region of Prion Protein Confers Resistance to Serum Deprivation
- Two Different Scrapie Prions Isolated in Japanese Sheep Flocks
- Design and syntheses of fluorescent labeled peptides related to human prion and their interaction to infected mice brain homogenate
- Pro-Oxidant Action of Pyrroloquinoline Quinone : Characterization of Protein Oxidative Modifications
- Application of Lysyl Oxidase Activity in Egg Shell Membrane of Hen to Selective Oxidation of ε-Amino Group in Lysine to Aldehyde in Short Peptides
- Repetitive Determination of Calcium Ion and Regeneration of a Chromogenic Reagent Using Chlorophosphonazo III and an Ion Exchanger in a Circulatory Flow Injection System
- Assessment of Prion Inactivation by Combined Use of Bacillus-Derived Protease and SDS
- Assessment of Prion Inactivation by Fenton Reaction Using Protein Misfolding Cyclic Amplification and Bioassay
- Intraspecies transmission of L-type-like bovine spongiform encephalopathy detected in Japan
- Covalent Binding of Tea Catechins to Protein Thiols : The Relationship between Stability and Electrophilic Reactivity
- Neuroanatomical Distribution of Disease-Associated Prion Protein in Cases of Bovine Spongiform Encephalopathy Detected by Fallen Stock Surveillance in Japan
- Human Serum Albumin as an Antioxidant in the Oxidation of (-)-Epigallocatechin Gallate : Participation of Reversible Covalent Binding for Interaction and Stabilization
- Production of Hydrogen Peroxide by Polyphenols and Polyphenol-rich Beverages under Quasi-physiological Conditions(Food & Nutrition Sience)
- A traceback phenomenon can reveal the origin of prion infection
- Design and Syntheses of Peptides as Bio-sensor Elements which can Detect the Structural Change of Prion Proteins
- A novel anti-prion protein monoclonal antibody and its single-chain fragment variable derivative with ability to inhibit abnormal prion protein accumulation in cultured cells
- 3B1346 RNAアプタマーがプリオンタンパク質を捕捉するメカニズム(3B 核酸結合蛋白質,日本生物物理学会第49回年会)
- Retrospective Analysis of Sheep Scrapie by Western Blotting with Formalin-Fixed Paraffin-Embedded (FFPE) Tissues
- Establishment of a Cell Line Persistently Infected with Chronic Wasting Disease Prions
- Sc237 hamster PrP^ and Sc237-derived mouse PrP^ generated by interspecies in vitro amplification exhibit distinct pathological and biochemical properties in tga20 transgenic mice
- Uptake dynamics of scrapie agent in the intestinal villous epithelium of suckling and weanling Syrian hamsters
- Strain-specific effects of reducing agents on the cell-free conversion of recombinant prion protein into a protease-resistant form