Assessment of Prion Inactivation by Combined Use of Bacillus-Derived Protease and SDS
スポンサーリンク
概要
- 論文の詳細を見る
Prions, infectious agents causing transmissible spongiform encephalopathy, retain infectivity even after undergoing routine sterilization processes. We found that MSK103 protease, identified in our previous study, effectively reduces infectivity and the level of misfolded isoform of the prion protein in scrapie-infected brain homogenates in the presence of SDS. The treatment therefore can be applied to the decontamination of thermolabile instruments.
- 社団法人 日本農芸化学会の論文
著者
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Yoshioka Miyako
Prion Disease Research Center, National Institute of Animal Health
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Murayama Yuichi
Prion Disease Research Center, National Institute of Animal Health
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Miwa Takehiro
Meiji Seika Kaisha Ltd.
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MIURA Katsuhiro
Japan Livestock Technology Association
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TAKATA Masuhiro
Prion Disease Research Center, National Institute of Animal Health
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YOKOYAMA Takashi
Prion Disease Research Center, National Institute of Animal Health
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NISHIZAWA Koji
Meiji Seika Kaisha Ltd.
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MOHRI Shirou
Prion Disease Research Center, National Institute of Animal Health
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