耳科手術後の感音難聴予防に対する抗ヒスタミン薬投与効果

概要

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A 36-year-old man who had undergone endolymphatic sac surgery suffered from sensorineural hearing loss in the same ear after breathing strongly through his nose and hearing a “pop”. Based on persistent dizzy spells and profound hearing loss, we made diagnosis of perilymphatic fistula and conducted exploratory tympanotomy. We closed the obvious round window fistula during surgery using fascia, reducing dizziness and sensorineural hearing loss. To prevent perilymphatic fistula after otological surgery, we administered olopatadine 10 mg/day for 2 weeks just after surgery. In comparison to cases not given olopatadine, those given postoperative olopatadine showed an apparent decrease in the incidence of profound sensorineural hearing loss, probably due to perilymphatic fistula.
2010-11-01