Significance of Early Onset and Progressive Increase of Activation Delay During Premature Stimulation in Brugada Syndrome
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概要
- 論文の詳細を見る
Background: The relationship between the activation delay during programmed stimulation and the inducibility of ventricular fibrillation (VF) and filtered QRS duration on signal-averaged ECG (SAECG) were assessed in patients with Brugada syndrome (BS). Methods and Results: The activation delay was assessed using the interval between the stimulus and the QRS complex during programmed stimulation in 25 patients with BS and 10 with idiopathic ventricular tachycardia (controls). The mean increase of delay (MID) was used to characterize the conduction curves. The filtered QRS duration (fQRSd) in leads V2 (RfQRSd) and V5 (LfQRSd) were also evaluated using SAECG. Both MIDs at the right ventricular outflow tract (RVOT) were significantly greater in symptomatic and asymptomatic BS patients than in the control group (symptomatic, 7.1 ±2.7 ms vs control, 2.5 ±1.2 ms, P<0.001, asymptomatic, 7.3 ±3.3 ms vs control, P<0.001, respectively). The MID correlated with the His-ventricular interval; however, there were no significant correlations between the MID and RfQRSd or RfQRSd - LfQRSd. Conclusions: The MID, which indicates an increase of the St-QRS during premature stimulation, was much greater in patients with BS (regardless of clinical symptoms) than in the control group, especially in the RVOT, which might be related to the easy inducibility of VF from the RVOT.
- 社団法人 日本循環器学会の論文
- 2009-07-20
著者
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Chinushi Masaomi
School of Health Science, Niigata University School of Medicine
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Aizawa Yoshifusa
First Department of Internal Medicine, Niigata University School of Medicine
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Furushima Hiroshi
First Department of Internal Medicine, Niigata University School of Medicine
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Furushima Hiroshi
新潟大学 医歯学総合研究科循環器学
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Furushima Hiroshi
Division Of Cardiology Niigata University Graduate School Of Medical And Dental Sciences
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Furushima Hiroshi
Divisions Of Cardiology
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Furushima Hiroshi
First Department Of Internal Medicine Niigata University School Of Medicine
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Furushima Hiroshi
Division Of Cardiology Hemotology And Endocrinology Niigata University Graduate School Of Medical An
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Chinushi Masaomi
Niigata School Of Health Science
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Chinushi Masaomi
First Department Of Internal Medicine Niigata University School Of Medicine
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Aizawa Y
Division Of Cardiology Niigata University Graduate School Of Medical And Dental Sciences
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IIJIMA Kenichi
First Department of Internal Medicine, Niigata University School of Medicine
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IZUMI Daisuke
First Department of Internal Medicine, Niigata University School of Medicine
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HOSAKA Yukio
First Department of Internal Medicine, Niigata University School of Medicine
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Iijima Kenichi
First Department Of Internal Medicine Niigata University School Of Medicine
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Izumi Daisuke
First Department Of Internal Medicine Niigata University School Of Medicine
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Hosaka Yukio
First Department Of Internal Medicine Niigata University School Of Medicine
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Honda Yasuyuki
Sado General Hospital
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相澤 好治
北里大学 医学部衛生学公衆衛生学
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Hosaka Yukio
Division Of Cardiology Niigata University Graduate School Of Medical And Dental Science
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Aizawa Yoshifusa
新潟大学 医学部保健学科
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Izumi Daisuke
Division Of Cardiology Niigata University Graduate School Of Medical And Dental Science
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相澤 好治
北里大医・衛生公衆
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Furushima Hiroshi
Division Of Cardiology Niigata University Graduate School Of Medical And Dental Science
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Aizawa Y
First Department Of Internal Medicine Niigata University Graduate School Of Medical And Dental Scien
-
相澤 好治
Dep. Of Preventive Medicine And Public Health Kitasato Univ. School Of Medicine
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Iijima Kenichi
Division Of Cardiology Niigata University Graduate School Of Medical And Dental Science
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相澤 好治
北里大学・医・衛生公衛
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Aizawa Yoshihusa
The First Department Of Internal Medicine Niigata University School Of Medicine Tachikawa Hospital T
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Aizawa Yoshifusa
Division Of Cardiology Hemotology And Endocrinology Niigata University Graduate School Of Medical An
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Aizawa Yosifusa
First Department Of Internal Medicine Niigata University School Of Medicine
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Aizawa Yoshifusa
Cardiovascular Medicine Niigata University Graduate School Of Medicine
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Aizawa Y
新潟大学 内科
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Fukunaga Hiroshi
Division Of Cardiology Niigata University Graduate School Of Medical & Dental Sciences
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Fujiwara Hiroshi
Division Of Cardiology Hemotology And Endocrinology Niigata University Graduate School Of Medical An
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Aizawa Yoshifusa
First Department Of Internal Medicine Niigata Universaity School Of Medicine
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Aizawa Yoshifusa
Division Of Endocrinology And Metabolism Department Of Homeostatic Regulation And Developments Niiga
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Aizawa Yoshifusa
Division Of Cardiology Hemotology And Endocrinology Niigata University Graduate School Of Medical An
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Aizawa Yoshifusa
Division Of Hematology Niigata University Medical And Dental Hospital
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Aizawa Yoshifusa
First Department Of Internal Medicine Niigata University Graduate School Of Medical And Dental Scien
-
Furushima Hiroshi
Divisions Of Dermatology Niigata University Graduate School Of Medical And Dental Sciences
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Chinushi Masaomi
Department Of Clinical Pharmacology Niigata College Of Pharmacology
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AIZAWA Yoshifusa
First Department of Internal Medecine, Niigata University School of Medicine, Niigata, Japan.
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