Imaging Endolymphatic Hydrops at 3 Tesla Using 3D-FLAIR with Intratympanic Gd-DTPA Administration
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概要
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Purpose: Visualization of endolymphatic hydrops by 3-dimensional fluid-attenuated inversion recovery-FLAIR using conventional turbo-spin-echo (3D-FLAIR-CONV) after intratympanic injection of Gd-DTPA has been reported in patients with Ménières disease. Compared to 3D-FLAIR-CONV used in previous studies, the addition of a variable flip-angle technique (3D-FLAIR-VFL) enables very long echo trains and, therefore, shorter scan times. We evaluated whether 3D-FLAIR-VFL could replace 3D-FLAIR-CONV in detecting endolymphatic hydrops after intratympanic Gd-DTPA administration. Methods: Eleven patients were included in this study. Twenty-four hours after Gd-DTPA injection, we performed 3D-FLAIR-CONV and 3D-FLAIR-VFL imaging at 3T. We compared the contrast-to-noise ratio (CNR) between cochlear fluid and the cerebellum between the 2 FLAIR sequences. We subjectively scored the size of the endolymphatic space in the cochlea and vestibule for each patient and correlated the scores with the clinical diagnoses. Results: The CNR of 3D-FLAIR-CONV was significantly higher than that of 3D-FLAIR-VFL. Scores for the size of endolymphatic space in the vestibule were identical between the 2 sequences; however, those in the cochlea disagreed in 3 cases. 3D-FLAIR-CONV correlated better with the clinical diagnoses. Conclusions: Currently, we may not be able to replace 3D-FLAIR-CONV with 3D-FLAIR-VFL, at least not with the scanning parameters used in the present study.
- 日本磁気共鳴医学会の論文
- 2008-06-01
著者
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伊藤 茂樹
名古屋大学医学部保健学科放射線技術学専攻
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深津 博
名古屋大学医学部放射線医学教室
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深津 博
名古屋大学放射線科
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深津 博
国立療養所鈴鹿病院 神経内科
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NAGANAWA Shinji
Department of Radiology, Nagoya University Graduate School of Medicine
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NAKASHIMA Tsutomu
Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine
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深津 博
名古屋大学医学部附属病院 放射線部
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SATAKE Hiroko
Department of Technical Radiology, Nagoya University Graduate School of Medicine
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Itoh Shigeki
Department Of Technical Radiology Nagoya University School Of Health Sciences
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深津 博
名古屋大学 医学部放射線科
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IWANO Shingo
Department of Radiology, Nagoya University Graduate School of Medicine
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SONE Michihiko
Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine
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FUKATSU Hiroshi
Department of Radiology, Nagoya University Hospital
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Fukatsu Hiroshi
Department Of Radiology Nagoya University Graduate School Of Medicine
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Fukatsu H
Tsukuba Research Institute Banyu Pharmaceutical Co. Ltd
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Nakashima Tsutomu
Department Of Otorhinolaryngology Nagoya University Graduate School Of Medicine
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Naganawa Shinji
Department Of Radiology Nagoya University Graduate School Of Medicine
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Iwano Shingo
Department Of Radiology Nagoya University Graduate School Of Medicine
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Satake Hiroko
Department Of Radiology Nagoya University Graduate School Of Medicine
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Sone Michihiko
Department Of Otorhinolaryngology Nagoya University Graduate School Of Medicine
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Fukatsu Hiroshi
名古屋大学医学部附属病院 放射線部
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Nakashima Tsutomu
Department Of Cardiology Nagoya University Graduate School Of Medicine
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Naganawa Shinji
Departments Of Radiology Nagoya National Hospital
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Satake Hiroko
Department of Radiology, Nagoya University Graduate School of Medicine
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