Transient Splenial Lesion of the Corpus Callosum after Acute Withdrawal of Antiepileptic Drug : A Case Report
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概要
- 論文の詳細を見る
Transient lesions at the splenium of the corpus callosum (SCC) have been reported after withdrawal of specific antiepileptic drugs (AED), though the pathophysiology of the lesions remains unclear. We examined and treated a schizophrenic patient who developed a transient SCC lesion after withdrawal of the AED, carbamazepine. Interestingly, the SCC lesion was accompanied by the onset of diabetes insipidus, a state of arginine-vasopressin (AVP) insufficiency. Because carbamazepine is shown to potentiate the effect of AVP, our case suggests that an insufficiency of AVP followed by withdrawal of AED could contribute to the pathogenesis of a transient SCC lesion.
- 日本磁気共鳴医学会の論文
- 2006-12-31
著者
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Sakamoto Takashi
Department of Cardiology, Kyoto prefectural Yosanoumi Hospital
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YUASA Tatsuhiko
Department of Neurology, National Centre of Neurology and Psychiatry, Kohnodai Hospital
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SATO Hideki
Department of Reparative Materials, Field of Tissue Engineering, Institute for Frontier Medical Scie
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Kamada Masaki
Department Of Neurosurgery Kawasaki Medical School
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HONDA KAZUHIRO
Department of Applied Chemistry, Kanagawa Institute of Technology
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Nemoto Hideaki
Department Of Neurology Kohnodai Hospital National Center Of Neurology And Psychiatry
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Yuasa Tatsuhiko
Department Of Neurology Kohnodai Hospital National Center Of Neurology And Psychiatry
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Sakamoto Takashi
Department Of Cardiology Kyoto First Red Cross Hospital
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Honda Kazuhiro
Department Of Neurology Kohnodai Hospital National Center Of Neurology And Psychiatry
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Honda Kazuhiro
Department Of Applied Chemistry Kanagawa Institute Of Technology
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NISHIMIYA Jin
Department of Neurology, Kohnodai Hospital, National Center of Neurology and Psychiatry
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MUNAKATA Maki
Department of Neurology, Kohnodai Hospital, National Center of Neurology and Psychiatry
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IWAMURA Akihide
Department of Neurology, Kohnodai Hospital, National Center of Neurology and Psychiatry
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Munakata Maki
Department Of Neurology Kohnodai Hospital National Center Of Neurology And Psychiatry
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Iwamura Akihide
Department Of Neurology Kohnodai Hospital National Center Of Neurology And Psychiatry
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Sakamoto Takashi
Department Of Aquatic Biosciences Tokyo University Of Fisheries
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Nishimiya Jin
Department Of Neurology Kohnodai Hospital National Center Of Neurology And Psychiatry
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Sakamoto Takashi
Department Of Neurology Kohnodai Hospital National Center Of Neurology And Psychiatry
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Sato Hideki
Department Of Applied Physics Graduate School Of Engineering Tohoku University
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Sato Hideki
Department Of Psychiatry Kohnodai Hospital National Center Of Neurology And Psychiatry
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Sato Hideki
Department of Applied Biology, Faculty of Textile Science, Kyoto Institute of Technology
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