No Circadian Changes of Heart Rate Turbulence Parameters in Patients with Myocardial Infarction
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概要
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<B>Background:</B> Heart rate turbulence (HRT) is a technique to identify patients at risk of cardiac mortality in patients with myocardial infarction (MI). However, little information is available concerning its circadian changes.<BR><B>Purpose:</B> The aim of the present study was to determine whether circadian changes in HRT parameters were found or not in post-MI patients.<BR><B>Methods:</B> We enrolled 37 post-MI patients (age 72±11, male 25). All patients underwent a 24-hour Holter electrocardiogram for assessing HRT. The determination of HRT was composed of two parameters: turbulence onset (TO) and turbulence slope (TS). In addition, we also calculated heart rate variability (HRV) variables. Circadian changes of each index were evaluated in the two time periods: daytime (9–21 h) and nighttime (21–9 h).<BR><B>Results:</B> The values of TO and TS were −0.32±0.72% and 2.14±2.09 ms/RRI, respectively during daytime and −0.25±0.90% and 2.41±2.44 ms/RRI, respectively at nighttime. No circadian changes were found in TO and TS. As regards HRV, SDNN and HF components represented lower values at nighttime than during daytime (<I>P</I>=0.04 and <I>P</I>=0.03, respectively).<BR><B>Conclusion:</B> In post-MI patients, no circadian changes were found in HRT parameters whereas they exist in some of HRV variables.
著者
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Ikeda Takanori
Department Of Cardiovascular Medicine Graduate School Of Medicine Kyoto University
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Yusu Satoru
Second Department Of Internal Medicine Kyorin University School Of Medicine
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Miwa Yosuke
Second Department Of Internal Medicine Kyorin University School Of Medicine
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Hoshida Kyoko
Second Department Of Internal Medicine Kyorin University School Of Medicine
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Abe Atsuko
Second Department Of Internal Medicine Kyorin University School Of Medicine
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Yoshino Hideaki
Second Department Of Internal Medicine Cardiology Kyorin University School Of Medicine
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Watanabe Takashi
Department Of Applied Physics Tohoku University
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Sato Hideki
Department of Applied Biology, Faculty of Textile Science, Kyoto Institute of Technology
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Kishino Tomonori
Department of Clinical Laboratory, Kyorin University Hospital
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