Transmural Dispersion of Repolarization Determines Scroll Wave Behavior During Ventricular Tachyarrhythmias : A Simulation Study
スポンサーリンク
概要
- 論文の詳細を見る
Background: Ventricular tachyarrhythmia is the leading cause of sudden cardiac death, and scroll wave re-entry is known to underlie this condition. Class III antiarrhythmic drugs are commonly used worldwide to treat ventricular tachyarrhythmias; however, these drugs have a proarrhythmic adverse effect and can cause Torsade de Pointes or ventricular fibrillation. Transmural dispersion of repolarization (TDR) has been suggested to be a strong indicator of ventricular tachyarrhythmia induction. However, the role of TDR during sustained scroll wave re-entry is poorly understood. The purpose of the present study was to investigate how TDR affects scroll wave behavior and to provide a novel analysis of the mechanisms that sustain tachyarrhythmias, using computer simulations. Methods and Results: Computer simulations were carried out to quantify the TDR and QT interval under a variety of IKs and IKr during transmural conduction. Simulated scroll wave re-entries were done under a variety of IKs and IKr in a ventricular wall slab model, and the scroll wave behavior and the filament dynamics (3-dimensional organizing center) were analyzed. A slight increase in TDR, but not in the QT interval, reflected antiarrhythmic properties resulting from the restraint of scroll wave breakup, whereas a marked increase in TDR was proarrhythmic, as a result of scroll wave breakup. Conclusions: The TDR determines the sustainment of ventricular tachyarrhythmias, through control of the scroll wave filament dynamics. (Circ J 2011; 75: 80-88)
- 2010-12-25
著者
-
Ikeda Takanori
Kyorin University Hospital
-
Aiba Takeshi
Department Of Cardiovascular And Respiratory Medicine Shiga University Of Medical Science
-
Ashihara Takashi
Department Of Cardiovascular And Respiratory Medicine Heart Rhythm Center Shiga University Of Medica
-
Ashihara Takashi
Department Of Cardiovascular Medicine Shiga University Of Medical Science
-
Nakazawa Kazuo
National Cardiovascular Cenfer Research Institute
-
Kurachi Yoshihisa
Department of Pharmacology II, Osaka University
-
Ikeda Takanori
The Second Department Of Internal Medicine Kyorin University School Of Medicine
-
Ikeda Takanori
Department Of Cardiovascular Medicine Graduate School Of Medicine Kyoto University
-
Arafune Tatsuhiko
National Inst. Of Advanced Industrial Sci. And Technol.
-
Arafune T
Graduate School Of Frontier Sciences The University Of Tokyo
-
Arafune Tatsuhiko
Inst. For Human Sci. & Biomed. Eng. National Inst. Of Advanced Industrial Science And Tech.
-
Arafune Tatsuhiko
名古屋大学環境医学研究所
-
Nakamura Kentaro
Second Department Of Internal Medicine Kyorin University School Of Medicine
-
Ikeda Takanori
Second Department of Internal Medicine, Kyorin University School of Medicine
-
Nakazawa Kazuo
Department Of Medical Technology Nagoya University School Of Health Sciences
-
Namba Tsunetoyo
Department Of Medical Technology Kagawa Prefectural College Of Health Sciences
-
Ikeda Takanori
Second Department Of Internal Medicine Kyorin University
-
Ikeda Takanori
Department Of Cardiovascular Medicine Kyoto University
-
Haraguchi Ryo
Laboratory Of Development And Evaluation Of Biomedical Instruments And Systems National Cardiovascul
-
MURAKAMI Shingo
Department of Otorhinolaryngology, Nagoya City University Medical School
-
Namba Tsunetoyo
Faculty Of Healthcare Sciences Himeji Dokkyo University
-
Kurachi Yoshihisa
Department Of Pharmacology Graduate School Of Medicine Osaka University
-
Haraguchi Ryo
National Cerebral And Cardiovascular Center Research Institute
-
TSUMOTO Kunichika
The Center for Advanced Medical Engineering and Informatics, Osaka University
-
Murakami Shingo
Department Of Neuro-otolaryngology Graduate School Of Medical Sciences Nagoya City University
-
Murakami Shingo
Department Of Pharmacology Graduate School Of Medicine Osaka University
-
Kurachi Yoshihisa
Department Of Cell Biology And Signaling Yamagata University School Of Medicine:department Of Pharma
-
Murakami Shingo
Department Of Neuro-otolaryngology Graduate School Of Medical Science Nagoya City University
-
Aiba Takeshi
Department Of Cardiovasculardynamics National Cardiovascular Center
-
Tsumoto Kunichika
The Center For Advanced Medical Engineering And Informatics Osaka University
-
Nakazawa Kazuo
National Cardiovascular Center Research Institute
-
Nakazawa Kazuo
National Cardiovascular Center, Research Institute
関連論文
- Effects of Intravenous Nifekalant as a Lifesaving Drug for Severe Ventricular Tachyarrhythmias Complicating Acute Coronary Syndrome
- PJ-577 The Antiplatelet Effect of Aspirin does not Change after 2-year Interval(PJ097,Cardiovascular Pharmacology (Clinical) (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- 1 Three-Year Outcome of the PRospective Evaluation of VENtricular Tachyarrhythmic Events and Sudden Cardiac Death in Patients with Left Ventricular Dysfunction (PREVENT-SCD) Study(Late Breaking Clinical Trials I,The 73rd Annual Scientific Meeting of The J
- Clopidogrel Resistance in Japanese Patients Scheduled for Percutaneous Coronary Intervention(Ischemic Heart Disease)
- Evaluation of the Antiplatelet Effects of Cilostazol, a Phosphodiesterase 3 Inhibitor, by VASP Phosphorylation and Platelet Aggregation
- PJ-422 Platelet Aggregability under Aspirin Therapy in Smoker is Higher than That in Non-smoker(Cardiovascular pharmacology, basic/clinical(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-421 Anti-platelet Effects of Statins in Patients under Aspirin Therapies(Cardiovascular pharmacology, basic/clinical(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- 5 Interim analyses of PRospective Evaluation of VENtricular Tachyarrhythmic events and Sudden Cardiac Death in patients with left ventricular dysfunction (PREVENT-SCD) study(Late Breaking Clinical Trials II,Special Program,The 72nd Annual Scientific Meeti
- Hydroxyzine, a First Generation H_1-Receptor Antagonist, Inhibits Human Ether-a-go-go-Related Gene (HERG) Current and Causes Syncope in a Patient With the HERG Mutation
- Differences in Vagal and Sympathetic Effects on Excitation Wave Dynamics of Paroxysmal Atrial Fibrillation : A Simulation Study
- Importance of Wavefront Organization and Widened Excitable Gap in Terminating Atrial Fibrillation by Pilsicainide
- Ischemia Induced Conduction Delay Plays a Key Role in Predisposing the Heart to Ventricular Fibrillation (Arrhythmia, Basic 5 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Estimation of Preload Recruitable Stroke Work Relationship from Steady-state Hemodynamics Without Recording Ventricular Pressure-volume Relationship(Cardiac Function, Basic/Clinical 1 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Soc
- Steep Repolarization Gradient in the Epicardium Develops Phase-2 Reentry and Subsequent Ventricular Tachyarrhythmias in a Model of the Brugada Syndrome(Arrhythmia, Basic 3 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-504 Sodium Channel Block with Pilsicainide Accentuates the Arrhythmogenic Substrate in a Model of the Brugada Syndrome(Arrhythmia, Basic 6 (A) : PJ84)(Poster Session (Japanese))
- PJ-494 High Resolution Optical Mapping of Cardiac Action Potentials in Freely Beating Rabbit Hearts(Arrhythmia, Basic 5 (A) : PJ83)(Poster Session (Japanese))
- Assessment of Atrioventricular Nodal Electrophysiological Characteristics After Radiofrequency Catherter Ablation of the Slow Pathway in Atrioventricular Nodal Reentrant Tachycardia : 3-Month Follow up
- -P239- THREE MONTHS FOLLOW-UP ASSESSMENT OF AV NODAL PHYSIOLOGY AFTER RADIOFREQUENCY CATHETER ABLATION OF SLOW PATHWAY IN AV NODAL REENTRANT TACHYCARDIA COMPARISON WITH WPW SYNDROME(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULA
- Dielectric effect during catheter ablation with microwave energy application in a myocardial phantom model
- RELATION BETWEEN THE SIZE OF LESIONS AND ARRHYTHMIAS PRODUCED BY MICROWAVE CATHETER ABLATION WITH A SPECIAL ELECTRODE DEVICE
- OPTIMAL FREQUENCY OF RADIOFREQUENCY CATHETER ABLATION IN VITRO AND IN VIVO FOR TREATING VENTRICULAR TACHYCARDIAS : A study using various frequencies
- WITHDRAWAL OF LONG-TERM ANTIARRHYTHMIC TREATMENT IN PATIENTS WITH FREQUENT VENTRICULAR ARRHYTHMIAS
- CLINICAL STUDY OF FREQUENCY DOMAIN ANALYSIS WITH USE OF THE P WAVE TRIGGERED SIGNAL-AVERAGED ELECTROCARDIOGRAMS FOR PREDICTING IN PATIENTS WITH PAROXYSMAL ATRIRIAL FIBRILLATION
- EVALIATION OF ARRHYTHMOGENICITY AND ABLATED LESION OF CATHETER ABLATION USING MICROWAVE ENERGY
- -0274-AN EXPERIMENTAL STUDY OF THE INFLUENCE ON THE MYOCARDIAL TISSUE AND ON THE TRICUSPID VENTRICULAR BLOCK BY RADIOFREQUENCY CATHETER ABLATION
- PJ-500 Coronary Artery Affects the Wave Propagation in a Thin Ventricular Myocardium : Study by the Optical Mapping and Computer Graphics Techniques(Arrhythmia, Basic 6 (A) : PJ84)(Poster Session (Japanese))
- 1 Three-Year Outcome of the PRospective Evaluation of VENtricular Tachyarrhythmic Events and Sudden Cardiac Death in Patients with Left Ventricular Dysfunction (PREVENT-SCD) Study(Late Breaking Clinical Trials I,The 73rd Annual Scientific Meeting of The J
- The Time Course of Recovery of Left Atrial Appendage Function Following Reversion of Chronic Atrial Flutter to Sinus Rhythm
- Analysis of Shock Accelerations by Dotting of One-handed Finger Braille(1E3 Mechanical Analysis & Its Applications)
- PE-491 Assessment of Circadian Variation in the Occurrence of Out-of-Hospital Cardiopulmonary Arrest with a Large Number of Japanese Patients(PE082,Ventricular Arrhythmia (Clinical/Diagnosis/Treatment) (A),Poster Session (English),The 73rd Annual Scientif
- DPJ-038 Physiological Pacing Site in the Right Ventricle : Alternative Mid-Septal Pacing is Superior Compered to Conventional Apical Pacing(DPJ07,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 2 (A),Digital Poster Session (Japanese),The 73rd Annual Sci
- OE-372 Heart Rate Turbulence as a Predictor of Cardiac Mortality and Arrhythmic Events in Patients with Ischemic or Nonischemic Dilated Cardiomyopathy(OE63,ECG/Body Surface Potential Mapping/Holter 1 (A),Oral Presentation (English),The 73rd Annual Scienti
- OE-243 Pathophysiology of the J Wave in Patients with Idiopathic Ventricular Fibrillation : Repolarization Abnormalities versus Conduction Disturbances(OE41,Ventricular Arrhythmia, Treatment (A),Oral Presentation (English),The 73rd Annual Scientific Meeti
- OE-120 Time-Domain T -Wave Alternans Measured from Holter Electrocardiograms Predicts Cardiac Mortality in Patients with Left Ventricular Dysfunction : A Prospective Study(OE21,ECG/Body Surface Potential Mapping/Holter 2 (A),Oral Presentation (English),Th
- PJ-771 J Waves on 12-Lead Electrocardiogram : Comparison between Patients with Syncope and Healthy Subjects(Arrhythmia, diagnosis / Pathophysiology / EPS(11)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Societ
- PJ-300 Visible T-Waves Variation after Treadmill Exercise Testing Predicts Cardiac Mortality in Post-Myocardial Infarction Patients with Preserved Cardiac Function(Exercise test/Cardiac rehabilitation(06)(H),Poster Session(Japanese),The 72nd Annual Scient
- PE-320 Assessment of Heart Rate Turbulence Determined on Holter Electrocardiogram in Predicting Future Cardiac Events : A Single Center Follow-up Study(ECG/Body surface potential mapping/Holter(04)(A),Poster Session(English),The 72nd Annual Scientific Mee
- OJ-026 Selective Site Pacing in the Right Ventricle : First Report of Pacing from Mid-Septum in Japan(Arrhythmia, therapy(05)(A),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OE-376 Evaluation of Right Ventricular Scar and Function Using Contrast-Enhanced Magnetic Resonance Imaging in Idiopathic Dilated Cardiomyopathy : Insight into Device Therapy(MRI/MRA(01)(I),Oral Presentation(English),The 72nd Annual Scientific Meeting of
- OE-279 Time-Domain T-Wave Alternans Predicts Cardiac Mortality in a Population Undergoing 24-Hour Holter Electrocardiogram : A Prospective Study(ECG/Body surface potential mapping/Holter(01)(A),Oral Presentation(English),The 72nd Annual Scientific Meeting
- 2 Risk Stratification Techniques for Sudden Cardiac Death in Patients with a Brugada-Type Electrocardiogram(Symposium 5 (SY-05) (A) New Findings of Mechanism and Therapeutic Strategies of Idiopathic Ventricular Fibrillation,Special Program,The 72nd Annual
- Risk Stratification for Sudden Cardiac Death(Ventricular Tachycardia/Fibrillation)
- PJ-289 Nifekalant Decreases Defibrillation Threshold of Electrical Cardioversion in Patients with Persistent Atrial Fibrillation(Arrhythmia, therapy-19, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-280 Myocardial Scar Detected by Contrast-Enhanced Magnetic Resonance Imaging and Arrhythmic Risk Stratification Markers in Patients with Nonischemic Cardiomyopathy(Arrhythmia, diagnosis/pathophysiology/EPS-13, The 71st Annual Scientific Meeting of the
- PE-048 Absence of Correlation between Spectral Method and Newly Developed Ambulatory Electrocardiogram-Based Time-Domain Method of T-Wave Alternans(ECG/Body surface potential mapping/Holter-3, The 71st Annual Scientific Meeting of the Japanese Circulation
- PE-028 Circadian Variation in the Occurrence of Out-of-Hospital Cardiopulmonary Arrest in a Japanese Population(Arrhythmia, diagnosis/pathophysiology/EPS-06, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- FRS-108 Identifying the Origin of Ventricular Arrhythmias Using 3D-Echocardiographic Tissue Tracking Imaging(Recent Advance in Cardiac Ultrasound, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Importance of V5R ST-elevation to Detect Right Ventricular Myocardial Infarction : Evaluation by Using Cardiac Magnetic Resonance Imaging(X-ray/CT/MRI/DSA 7 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-274 Discrepancy of Necrosis Size and Transmural Extent in Small-Sized Myocardial Infarction Evaluated by Contrast-Enhanced Magnetic Resonance Imaging(X-ray/CT/MRI/DSA5 (I) : PJ46)(Poster Session (Japanese))
- PJ-273 Visualization of Ventricular Thrombi With Contrast-Enhanced Magnetic Resonance Imaging in Patients With an Anterior-Apical Myocardial Infarction(X-ray/CT/MRI/DSA5 (I) : PJ46)(Poster Session (Japanese))
- OJ-012 Mutation Analysis for the Human Cardiac Ryanodine Receptor Gene (RyR2) in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)(Arrhythmia, diagnosis/pathophysiology/EPS-03, The 71st Annual Scientific Meeting of the Japanese Circulation Soci
- FRS-052 Identification and Functional Characterization of a Novel Intronic Splicing Mutation in KCNQ1 Associated with Long QT Syndrome(FRS11,New Insights into Basic Mechanisms of Arrhythmia (A),Featured Research Session (English),The 73rd Annual Scientifi
- Dynamic Change in ST-Segment and Spontaneous Occurrence of Ventricular Fibrillation in Brugada Syndrome With a Novel Nonsense Mutation in the SCN5A Gene During Long-Term Follow-up
- Mutation Site Dependent Variability of Cardiac Events in Japanese LQT2 Form of Congenital Long-QT Syndrome
- Effects of Landiolol, an Ultra-Short-Acting β_1-Selective Blocker, on Electrical Storm Refractory to Class III Antiarrhythmic Drugs
- Quantitative assessment of cibenzoline administration for vagally mediated paroxysmal atrial fibrillation using frequency-domain heart rate variability analysis
- PE-024 Prevalence of Brugada-Type Electrocardiograms with Class IC Antiarrhythmic Drugs in Patients with Paroxysmal Atrial Tachyarrhythmias : Pilsicainide versus Propafenone(Arrhythmia, diagnosis/pathophysiology/EPS-05, The 71st Annual Scientific Meeting
- PE-020 Noninvasive Strategies in Unmasking Brugada Syndrome : Full Stomach Test versus Pharmacological Test(Arrhythmia, diagnosis/pathophysiology/EPS-05, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-276 Lower Efficacy of Aspirin in Diabetic Patients(Thromboembolism/Antithrombotic therapy/Thrombolysis-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Noninvasive Characterization of Intra-Atrial Reentrant Tachyarrhythmias After Surgical Repair of Congenital Heart Diseases(Arrhythmia/Electrophysiology)
- PE-010 Moderate Hypothermia Destabilized Spiral Waves without Widening Excitable Gap in Favor of Self-termination of Ventricular Tachycardia/Fibrillation(Arrhythmia, basic(03)(A),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese C
- PE-017 Moderate Hypothermia Causes Destabilization of Rotors without Wavelength Shortening in Favor of VT/VF Self-Termination(Arrhythmia, basic-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OE-238 Mechanisms of Global and Regional Cooling-Assisted Defibrillation in a Bidomain Ventricular Model(Arrhythmia, basic-1 (A) OE40,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Acute Amiodarone Suppresses Action Potential Alternans in the Two-dimensional Ventricular Myocardium of Rabbit Hearts(Arrhythmia, Basic 4 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Action Potential Dynamics of Spiral-type Reentry in 2-Dimensional Anisotropic Layer of Ventricular Muscle : Optical Mapping Analysis Using High-fidelity CMOS Camera(Arrhythmia, Basic 3 (A), The 69th Annual Scientific Meeting of the Japanese Circulation So
- 5 Noninvasive Risk Stratification of Subjects with a Brugada-Type Electrocardiogram and No Past History of Cardiac Arrest(Brugada Syndrome:From Cell to Bedside,Plenary Session 2 (PL2) (A),The 70th Anniversary Annual Scientific Meeting of the Japanese Circ
- PE-031 Predictive Value of Microvolt T-Wave Alternans for Sudden Cardiac Death in Patients with Preserved Cardiac Function after Acute Myocardial Infarction(Arrhythmia, diagnosis/pathophysiology/EPS-06, The 71st Annual Scientific Meeting of the Japanese C
- Initial Stage of Oxidation of Hydrogen-Termimated Si(100)-2×1 Surface
- Predictive value of microvolt T-wave alternans for sudden cardiac death in patients with preserved cardiac function after acute myocardial infarction : Results of a collaborative cohort study
- PE-141 Effects of Amiodarone and Bepridil, Multi-channel Blockers, on Spiral Wave Reentries in Human Atrial Model with Electrical and Structural Remodelings(Arrhythmia, therapy(07)(A),Poster Session(English),The 72nd Annual Scientific Meeting of the Japan
- OE-383 Electrode Potential is Available for Evaluating the Local Repolarization during Fibrillation(ECG/Body surface potential mapping/Holter-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Amiodarone Organizes Multiple Wavelets into Simple Spiral Reentry-by New Protocol for Automatically Visualizing Activation Propagation from "Electrode Mapping"(Arrhythmia, Pharmacological Therapy 4 (A), The 69th Annual Scientific Meeting of the Japanese C
- Clinical Usefulness of the Combination of T-Wave Alternans and Late Potentials for Identifying High-Risk Patients With Moderately or Severely Impaired Left Ventricular Function
- Combined assessment of T-wave alternans and late potentials used to predict arrhythmic events after myocardial infarction : A prospective study
- Resuscitation from Out-of-Hospital Cardiac Arrest Using External Defibrillators by Emergency Medical Service Staffs in Japan : A Single Medical Center Study(Arrhythmia, Non-pharmacological Therapy 8 (A), The 69th Annual Scientific Meeting of the Japanese
- Prevalence of Brugada-Type Electrocardiograms with Class IC Antiarrhythmic Drugs in Patients with Paroxysmal Atrial Tachyarrhythmias but no Risk-Stratifying Factors(ECG/Body Surface Potential Mapping/Holter 2 (A), The 69th Annual Scientific Meeting of the
- Risk Management Using Microvolt T-Wave Alternans Testing in Patients with Impaired Left Ventricular Function(Sudden Cardiac Death : Current Status and Preventive Measures, The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-215 Antiarrhythmic efficacy of nifekalant to rescue from life-threatening polymorphic ventricular tachycardia/ventricular fibrillation associated with acute myocardial ischemia(Arrhythmia, Pharmacological Therapy 3 (A) : PJ36)(Poster Session (Japanese)
- Biatrial Pacing for Paroxysmal Atrial Fibrillation : The Outcome and Electrophysiological Mechanism of Prevention
- Prevention of Atrial Fibrillation using an Implantable Pacemaker : Crossover Trial between Bi-Atrial and Conventinal Right Atrial Pacing
- Comparison of Various Prognostic Valuables Including T-Wave Alternans in Predicting Arrhythmic Events During Long-Term Follow-up After Myocardial Infarction
- Evaluation of Bi-Atrial Pacing and Single Site Right Atrial Pacing for the Prevention of Atrial Fibrillation
- Atrial Double Potentials Associated With the Elimination of the Electrical Connection Between the Coronary Sinus (CS) and the Left Atrium in Two Cases of Wolff-Parkinson-White Syndrome With a CS-Connected Accessory Pathway
- PJ-294 Clinical Significance of the Admission Electrocardiogram QRS Duration in Acute Myocardial Infarction(Acute myocardial infarction, clinical (diagnosis/treatment)-8 (IHD) PJ50,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting o
- OJ-378 Beat-to-beat Variation of T Waves "T-Wave Modulation" as a Harbinger of Cardiac Rupture after Acute Myocardial Infarction(ECG/Body surface potential mapping/Holter-3 (A) OJ63,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeti
- PE-027 Relevance of J Wave in the Inferior and/or Left Lateral Leads in Patients with Syncope and no Apparent Heart Disease(Arrhythmia, diagnosis/pathophysiology/EPS-7 (A) PE5,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the
- PE-361 Useful Noninvasive Strategy to Detect Life-Threatening Events in Subjects with the Brugada-type Electrocardiogram : A Prospective Study(ECG/Body Surface Potential Mapping/Holler 7 (A) : PE62)(Poster Session (English))
- QT Dispersion as a Predictor for Subsequent Cardiac Events After Rotational Atherectomy : A Prospective study
- 2 Effects of Antiarrhythmic Drugs on Electrophysiological Action and Wavefront Dynamics During Atrial Fibrillation(Plenary Session 3 (PL3) (A) : Atrial Fibrillation : From bench to bedside)(Special Program)
- Statement for the Optimal Use of Home Electrocardiography 2007
- Circadian Variation in Out-of-Hospital Cardiac Arrests due to Cardiac Cause in a Japanese Patient Population
- Rotational Atherectomy Increases QT Dispersion Compared with Mere Stent Implantation
- The Refractory Gradient Increases the Incidence of VT/VF Induced by Sodium Channel Blockers
- Conversion of Multiple Non-Stationary Wavefronts to a Single Stationary Reentrant Wavefront by a Pure Ikr Channel Blocker in Canine Atria
- Noninvasive Strategies in Identifying Patients at Risk for Life-Threatening Arrhythmic Events
- Afterdepolarizations Promote the Transition From Ventricular Tachycardia to Fibrillation in a Three-Dimensional Model of Cardiac Tissue
- Differences in the R on T Phenomena Degenerating into VT/NF by between PVC and Catheter Pacing : A Simulation Study
- Transmural Dispersion of Repolarization Determines Scroll Wave Behavior During Ventricular Tachyarrhythmias : A Simulation Study
- Guidelines for Risks and Prevention of Sudden Cardiac Death (JCS 2010) : Digest Version
- Mortality Rate of Japanese SCD-HeFT or MADIT-II Criteria Population: Sub-Analysis from the PREVENT-SCD