Evaluation of Bi-Atrial Pacing and Single Site Right Atrial Pacing for the Prevention of Atrial Fibrillation

概要

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Atrial resynchronization resulting from simultaneous pacing of the atria may adjust inter- or intra-atrial asynchrony and prevent atrial fibrillation(AF). The purpose of this study was to assess the effioacy of bi-atrial pacing(BAP)in preventing AF, and the safety of this system. The effect of BAP was compared with single site right atrial pacing(RAP)in 6 patients with sick sinus syndrome and paroxysmal AF in a prospective switchover trial. P wave duration was significantly reduced during BAP(p<0.01). Pacing threshold, atrial wave amplitude and the lead impedance presented no significant differences at implant, 1 week and 3 months after implantation, respectively(NS). The number of AF episodes significantly decreased during both RAP and BAP compared with the control(p<0.01). Although the number of premature atrial contractions was significantly less during BAP than RAP(p<0.05), there were no significant differences of AF episodes between the two. The percentage of pacing was achieved in only 70% during both pacing modes. BAP was safe and reliable in this follow-up period and can prevent AF. These findings provide encouragement for further study and observation of BAP to prevent AF.
社団法人日本循環器学会の論文
2001-12-20