Biomimetic Synthesis of Gramicidin S, Direct Formation of the Antibiotic from Pentapeptides Related to Gramicidin S on Solid Support

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概要

• 論文の詳細を見る
• 2005-03-01

著者

• ISHII Rie

  Department of Laboratory Animal Science, The Tokyo Metropolitan Institute of Medical Science

• Ishii Rie

  Department Of Chemistry Toho University

• TAMAKI Makoto

  Department of Chemistry, Faculty of Science, Toho University

• KOHGI Momoko

  Department of Chemistry, Toho University

• NISHIWAKI Saeko

  Department of Chemistry, Toho University

• Kohgi Momoko

  Department Of Chemistry Toho University

• Tamaki Makoto

  Department Of Chemistry Toho University

• Tamaki Makoto

  Department Of Chemistry And Biomolecular Science Toho University

• Nishiwaki Saeko

  Department Of Chemistry Toho University

• Ishii Rie

  Department Of Analytical Chemistry Faculty Of Pharmaceutical Sciences Hoshi University

関連論文

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• A Novel Active Analogue of Gramicidin S with Smaller Ring Size
• Syntheses of Cyclic Peptides Containing 4-cis-Amino-L-Proline
• Synthesis and Properties of Gramicidin S Analogues with Smaller Ring Size
• Biomimetic Cyclization of Linear Peptides Related to Gramicidin S with Several Lengths on Solid Support
• Biomimetic Synthesis of Gramicidin S, Direct Formation of the Antibiotic from Pentapeptides Related to Gramicidin S on Solid Support
• Solvent-Dependent Conformations of Cyclic Tetrapeptide. II
• γ-Functional Prolines Based on Naturally Occurred Hydroxyproline. III
• γ-Functional Prolines Based on Naturally Occurring Hydroxyproline. II
• Syntheses and Properties of Gratisin Analogues Containing Ala Residue
• Syntheses of Gramicidin S Analogues Consisting of Eleven Amino Acid Residues
• Conformation of Cyclic Tetrapeptides Containing Two Pro Residues
• Syntheses of Gramicidin S Analogues Containing Cis-D-Phe-Pro Peptide Bond
• Novel Antimicrobial Gratisin Analogues Containing Various D-Amino Acid Residues in Place of D-Tyr Residues
• Syntheses of Active Gramicidin S Analogues without Amphiphilic Conformation. II
• A Novel Polycationic Analogue of Gratisin with Antibiotic Activity against both Gram-positive and Gram-negative Bacteria
• Syntheses of Active Gramicidin S Analogs without Amphiphilic Conformation
• A Novel, Antimicrobially Active Analog of Gramicidin S without Amphiphilic Conformation
• Synthesis and Properties of Cyclic Peptides Containing α,δ-Diaminovaleric Acid Linker
• Relationship between the Cyclization and Conformation of Pentapeptide Active Esters Related to Gramicidin S Having No Protecting Group on the Side Chain of the Ornithine Residue
• Cyclization of Hexapeptide Active Esters Related to Gratisin Having No Protecting Group on the Side Chain of Ornithine Residue
• Practical Synthesis of 4-cis Hydroxy-L-Proline
• Conformational Analysis of a Peptide Antibiotic "Gratisin"
• Cyclization of Pentapeptide Related to Gramicidin S without Protection of δ-Amino Group of the Ornithine Residue on Solid Support
• γ-Functional Prolines Based on Naturally Occurring Hydroxyproline.
• 新規自然発症ミオシン6-nullマウスの表現型および発現解析
• Conformational Analysis of a Peptide Antibiotic "Gratisin". II
• Syntheses and Conformational Analyses of Cyclic Peptides Containing 4-cis-Amino-L-Proline. II
• Antimicrobially Active Analogues of Gramicidin S Having Fatty Acyl Moiety
• Syntheses of Novel Cyclic Undecapeptides Related to Gramicidin S with D-Phe-X-Pro Sequences
• Hybrid Analogues of Gramicidin S and Gratisin
• Syntheses and Properties of Cyclic Tetrapeptides Containing α, δ-Diaminovaleric Acid and α, ε-Diaminocaproic Acid Linkers
• Polycationic Gramicidin S Analogues with Both High Antibiotic Activity and Very Low Hemolytic Activity
• Synthesis of Novel Fatty-Acyl Gratisin Derivatives
• Design and syntheses of gramicidin S analogs, cyclo(-X-Leu-X-D-Phe-Pro-)_2 (X=His, Lys, Orn, Dab and Dap)
• Gramicidin S analogs having six basic amino acid residues
• Novel Cycloundecapeptides Related to Gramicidin S with Both High Antibiotic Activity and Low Hemolytic Activity
• Synthesis and properties of gramicidin S analogs containing D-Phe-L-Pro-D-Val or L-Phe-L-Pro-D-Val sequences in place of D-Phe-L-Pro-L-Val sequence in the .BETA.-turn part of the antibiotic.
• Studies on the Secondary Structure of Bradykinin in Aqueous Solution. Syntheses, Circular Dichroism Spectra, and Biological Activities of Bradykinin Analogs Containing 5-Aminovaleric Acid Residue.
• Possible interpretation of inactivity of novel gramicidin S analogs by CD spectral analysis of tetrapeptide derivatives related to the analogs.
• Synthesis and properties of gramicidin S analogs containing D-Lys residue in place of Orn residue.

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