Microparticle Enzyme Immunoassay (MEIA)法によるジゴキシン血中濃度測定の評価

概要

論文の詳細を見る
The clinical usefulness of a microparticle enzyme immunoassay (MEIA) method for the determination of dogoxin in serum was investigated. The inter-and intra-assay reproducibilities of this method were 2.4 to 4.9% and 3.8 to 6.2% (C.V.%), respectively.In the determination of serum digoxin levels. MEIA well correlated with fluorescence polarization immunoassay (FPIA) (r= 0.942, n=153). Cross reaction by various drugs used concomitantly with digoxin was not detected in the MEIA assay. Moreover,endogenous digoxin-like immunoreactive substance was not detected in serum from newborns (n=24) or patients with renal failure (n=42) who were not taking digoxin.
日本医療薬学会の論文
1997-10-10