Linkage Mapping of the Locus Responsible for Male Pseudohermaphroditism (mp) on Rat Chromosome 7

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概要

• 論文の詳細を見る

• TF is a mutant rat strain showing male pseudohermaphroditism controlled by an autosomal single recessive gene (mp). The affected rats show lack of Leydig cells and androgen deficiency. In this study, we performed linkage analysis using F2 progeny of crosses between TF and BN strains to determine the chromosomal localization of the mp locus. The mp locus was mapped in a 4 cM region of the distal region of rat chromosome 7 between D7Rat3 and D7Rat115 or D7Rat94. Comparison of the linkage map with corresponding regions of the published rat genome sequence revealed several candidate genes for the mp mutation, including the Dhh, Tegt, Gdp3, and Amhr2 genes.

• 社団法人　日本実験動物学会の論文

著者

• Kobayashi Eiji

  自治医科大学 薬理学

• Kobayashi E

  Jichi Medical School Tochigi Jpn

• Kobayashi Eiji

  National Livestock Breeding Center

• NOGUCHI Junko

  Genetic Diversity Department, National Institute of Agrobiological Sciences

• KAWAI Yasuhiro

  Graduate School of Natural Science and Technology, Okayama University

• KUNIEDA Tetsuo

  Graduate School of Natural Science and Technology, Okayama University

• TAKENO Yuriko

  Graduate School of Natural Science and Technology, Okayama University

• TACHIBANA Motokazu

  Imamichi Institute for Animal Reproduction

• WAKAFUJI Yasumasa

  Imamichi Institute for Animal Reproduction

• Kunieda T

  Graduate School Of Natural Science And Technology Okayama University

• Kunieda Tetsuo

  Graduate School Of Natural Sci. And Technol. Okayama Univ.

• Takeno Yuriko

  Graduate School Of Natural Science And Technology Okayama University

• 立花 資和

  Imamichi Institute For Animal Reproduction

• Noguchi J

  Division Of Animal Sciences National Institute Of Agrobiological Sciences

• Noguchi Junko

  Positron Medical Center Tokyo Metropolitan Institute Of Gerontology

• Kawai Yasuhiro

  Graduate School Of Natural Science And Technology Okayama University

• KUNIEDA Tetsuo

  Graduate School of Environmental and Life Science, Okayama University, 1-1-1 Tsushima-Naka, Kita-ku, Okayama 700-8530, Japan

• KUNIEDA Tetsuo

  Graduate School of Environmental and Life Science, Okayama University

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