A Genetic Linkage Map of Rat Chromosome 9 with a New Locus for Variant Activity of Liver Aldehyde Oxidase
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概要
- 論文の詳細を見る
A genetic linkage map of rat chromosome 9 consisting of five loci including a new biochemical marker representing a genetic variation of the activity of the liver aldehyde oxidase, (Aox) was constructed. Linkage analysis of the five loci among 92 backcross progeny of (WKS/Iar × IS/Iar)F1 × WKS/Iar revealed significant linkages between these loci. Minimizing crossover frequency resulted in the best gene order: Aox-D9Mit4-Gls-Cryg-Tp53l1. The homologues of the Cryg, Gls, and Aox genes have been mapped on mouse chromosome 1 and human chromosome 2q. The present findings provide further evidence for the conservation of synteny among these regions of rat, mouse, and human chromosomes.
- 社団法人 日本実験動物学会の論文
著者
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Kobayashi Eiji
自治医科大学 薬理学
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Kobayashi E
Jichi Medical School Tochigi Jpn
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Kobayashi Eiji
National Livestock Breeding Center
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TACHIBANA Motokazu
Imamichi Institute for Animal Reproduction
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KUNIEDA Tetsuo
Faculty of Agriculture, Okayama University
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IKADAI Hiroshi
Dolittle Animal Clinic
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Kunieda T
Graduate School Of Natural Science And Technology Okayama University
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Kunieda Tetsuo
Graduate School Of Natural Sci. And Technol. Okayama Univ.
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Kunieda Tetsuo
Faculty Of Agriculture Okayama University
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Ikadai H
Dolittle Animal Clinic
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立花 資和
Imamichi Institute For Animal Reproduction
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