Design of Chiral Catalysis and Asymmetric Autocatalysis for the Enantioselective Additions of Organozinc Reagents
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概要
- 論文の詳細を見る
Diphenyl(1-methylpyrrolidin-2-yl)methanol (DPMPM) and N, N-dibutylnorephedrine (DBNE) are highly enantio- and chemoselective chiral catalysts for the addition of dialkylzincs to various aldehydes, affording sec-alcohols with high enantiomeric excesses. Heterogeneous chiral catalyst supported on polystyrene is also highly enantioselective. Pyrimidyl and quinolyl alkanols are asymmetric autocatalysts with amplification of enantiomeric excess in the enantioselective isopropylation of aldehydes. Enantioselective addition of dialkylzincs to N-diphenylphosphinylimines and conjugate addition to enones are performed using N, N-dialkylnorephedrines.
- 社団法人 有機合成化学協会の論文
- 1997-11-01
著者
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Shibata T
Department Of Chemistry Faculty Of Science And Engineering Waseda University
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ソウ合 憲三
東京理大 理
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Soai Kenso
Department Of Applied Chemistry Faculty Of Science Science University Of Tokyo
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Shibata Takanori
Department Of Chemistry Faculty Of Science Okayama University
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Shibata Takanori
Department Of Chemistry And Biochemistry School Of Advanced Science And Engineering Waseda University
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