Stereoselectivity in the reduction of cyclic ketones with sodium borohydride. Effect of the ratio of the components of a mixed solvent of tetrahydrofuran and methanol.
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概要
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Reduction of relatively conformationally rigid cyclic ketones with sodium borohydride was examined in a mixed solvent of tetrahydrofuran(THF) and methanol(MeOH) with varying the ratio of the components. The highest stereoselectivities of the reductions were observed in the <I>mixed solvent</I>, and not in each <I>individual solvent</I>.
- 公益社団法人 日本化学会の論文
著者
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Soai Kenso
Department Of Applied Chemistry Faculty Of Science Science University Of Tokyo
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Ohi Kazumi
Department of Applied Chemistry, Faculty of Science, Science University of Tokyo
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