Cationic Iridium-Catalyzed Synthesis Initiated by the Cleavage of C-H, N-H, and C-O Bonds
スポンサーリンク
概要
- 論文の詳細を見る
The direct functionalization of inactive bonds is an ideal transformation in organic synthesis because the introduction of activating groups, such as halogens and metals, to substrates is unnecessary and by-products derived from them are not formed. This report describes several types of cationic iridium-catalyzed reactions that occur through C-H, N-H, or C-O bond cleavage. The carbonyl-directed sp2 C-H bond activation of aryl ketones realized new approaches to benzofulvene, benzofuran and indole synthesis, as well as the C2-position-selective alkylation of N-acyl-protected indoles. The enantioselective sp3 C-H alkylation of 2-(alkylamino)pyridines and the intermolecular enantioselective hydroamination of heteroaromatic amines gave various chiral amines. O-to-N-alkyl migration in 2-alkoxypyridines gave N-alkylpyridones via C-O bond cleavage.
- 社団法人 有機合成化学協会の論文
著者
-
Tsuchikama Kyoji
Department Of Chemistry School Of Science And Engineering Waseda University
-
Shibata Takanori
Department Of Chemistry And Biochemistry School Of Advanced Science And Engineering Waseda University
-
SHIBATA Takanori
Department of Chemistry and Biochemistry, School of Advanced Science and Engineering, Waseda University
-
Pan Shiguang
Department of Chemistry and Biochemistry, School of Advanced Science and Engineering, Waseda University
-
Tsuchikama Kyoji
Department of Chemistry and Biochemistry, School of Advanced Science and Engineering, Waseda University
関連論文
- Antineutrophil cytoplasmic antibodies in patients with Graves' disease : association of antimyeloperoxidase autoantibodies with propylthiouracil therapy
- Microscopic polyangiitis after silicone breast implantation
- Adjuvant-induced macrophage-dominant nephrotoxic serum nephritis in rats
- Propylthiouracil-induced antineutrophil cytoplasmic antibody-associated crescentic glomerulonephritis in a patient with a predisposition to autoimmune abnormalities
- Palladium-Catalyzed Synthesis of Biaryls from Arylzinc Compounds Using N-Chlorosuccinimide or Oxygen as an Oxidant
- Application of Neural Network-Based Servo Controller to Position, Force and Stabbing Control by Robotic Manipulator
- An Immunohistochemical Study of the Localization of Types I, II and III Collagen in the Temporomandibular Joint of Growing Monkeys
- Discovery and Development of Asymmetric Autocatalysis
- Asymmetric Autocatalysis of Pyrimidyl Alkanol Induced by Optically Active 1,1'-Binaphthyl, an Atropisomeric Hydrocarbon, Generated from Spontaneous Resolution on Crystallization
- Organic Field-effect Transistor Based on a Thin Film of Polydiacetylene Prepared from 10,12-Pentacosadiynoic Acid
- Expression of Nerve Growth Factor and Neurturin, and Their Receptors in Mouse Taste Buds
- Intermolecular Allene-Alkyne Coupling Reactions by the Use of Fe(CO)_4(NMe_3)
- The Reaction of Butatrienolates with Aldehydes for the Syntheses of α-Vinylidene Acylsilanes
- Cationic Au(I)- and Pt(II)-Catalyzed Silylation of Alcohols Using Allylsilanes
- Design of Chiral Catalysis and Asymmetric Autocatalysis for the Enantioselective Additions of Organozinc Reagents
- Conversion of 1-(ω-Alkynyl)-1, 2-propadienyl Sulfides to Bicyclic Dienones by the Use of Iron Carbonyl Complex
- A Fulminant Case of Renal Vein Thrombosis in a Patient with Autoimmune Disorder and Membranous Nephropathy
- Stereoselective Synthesis of Allylsilanes Bearing Tetrasubstituted Olefin via 2,2-Diborylethylsilane
- Cationic Iridium-Catalyzed Synthesis Initiated by the Cleavage of C-H, N-H, and C-O Bonds