The Effect of Tulobuterol Tape on Histamine-Induced Bronchoconstriction in Conscious Guinea Pigs:Long Duration of Action
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概要
- 論文の詳細を見る
The objective of the present study was to determine the action duration of tulobuterol tape within a 24-hr period in conscious guinea pigs. The bronchoconstriction induced by histamine-inhalation was significantly inhibited by tulobuterol tape in comparison with its placebo tape 8 and 12 hr after binding, and the inhibitory rate was 50±11% and 35±13%, respectively. Twenty-four hours after binding, the inhibitory effect of tulobuterol tape gradually diminished, but the inhibitory rate was maintained at 30±14%. These results suggests that tulobuterol tape has a long lasting bronchodilatory action.
- 社団法人 日本薬理学会の論文
- 1999-03-01
著者
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Musoh K
Hokuriku Seiyaku Co. Ltd. Fukui Jpn
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Kato K
Grad. Sch. Pharm. Sci. Nagoya City Univ.:okazaki Inst. Integ. Biosci. Natl. Inst. Natl. Sci.
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Kato H
Research And Development Headquarters Hokurikit Seiyaku Co. Ltd.
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Kato H
Teikyo Univ. Kanagawa Jpn
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OHASHI Tetsuo
Research and Development Division, Hokuriku Seiyaku Co., Ltd.,
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KATO Hideo
Research and Development Division, Hokuriku Seiyaku Co., Ltd.,
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IWANAGA Yuji
Research and Development Headquarters, Hokurikit Seiyaku, Co., Ltd.
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MORIKAWA Kouji
Research and Development Headquarters, Hokurikit Seiyaku, Co., Ltd.
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MUSOH Keiichi
Research and Development Division, Hokuriku Seiyaku Co., Ltd
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KAWAMURA Kayoko
Research and Development Division, Hokuriku Seiyaku Co., Ltd
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MIYAKE Isao
Research and Development Division, Hokuriku Seiyaku Co., Ltd
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SHIMADA Shino
Research and Development Division, Hokuriku Seiyaku Co., Ltd
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Shimada Shino
Research And Development Division Hokuriku Seiyaku Co. Ltd
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Kawamura Kimio
Research And Development Division Hokuriku Seiyaku Co. Ltd
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Kato Hideo
Research And Development Division Hokuriku Seiyaku Co. Ltd.
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垣内 正人
Research And Development Division Hokuriku Seiyaku Co. Ltd
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Miyake Isao
Research And Development Division Hokuriku Seiyaku Co. Ltd
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Iwanaga Y
Research And Development Headquarters Hokurikit Seiyaku Co. Ltd.
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Morikawa Kouji
Research And Development Headquarters Hokurikit Seiyaku Co. Ltd.
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Ohashi Tetsuo
Research And Development Division Hokuriku Seiyaku Co. Ltd
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Iwanaga Yuji
Research And Development Headquarters Hokurikit Seiyaku Co. Ltd.
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Kato Hideo
Yamaguchi Univ. Yamaguchi Jpn
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Morikawa Kouji
Research and Development Division, Hokuriku Seiyaku, Co., Ltd.
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Iwanaga Yuji
Research and Development Division, Hokuriku Seiyaku, Co., Ltd.
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