Kobayashi Shigeki | Division Of Analytical Chemistry Of Medicines Showa Pharmaceutical University

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著作論文

Products of Thymine Oxygenation by a Non-heme Oxygenation Model, FeII(MeCN)62+–Ac2O–H2O2, and the Transition State Model between Oxoiron and Thymine
PJ-375 Carperitide, Atrial Natriuretic Peptide, Improves Hemoglobin Level in Acute Heart Failure(PJ063,Heart Failure (Treatment) 1 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
PJ-068 Abnormally Tight Domain-Domain Interaction at Mutation Site could be a Primary Cause of Catecholaminergic Polymorphic Ventricular Tachycardia(PJ012,Calcium Handling, Cardiac Function (Basic) (M),Poster Session (Japanese),The 73rd Annual Scientific
PJ-203 Dantrolene, a therapeutic agent for malignant hyperthermia, inhibits catecholaminergic polymorphic ventricular tachycardia : Insights from a RyR2 R2474S/+ knock-in mouse model(Arrhythmia, basic(05)(A),Poster Session(Japanese),The 72nd Annual Scient
FRS-017 Enhanced Sensitivity of the Cardiac Ryanodine Receptor to Activation by Luminal Ca^ as a Primary Cause of CPVT(New Insights into Basic Mechanism of Arrhythmia(A),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circ
PJ-765 Scavenging Free Radicals by Low-dose Carvedilol Prevents Redox-dependent Ca^ Leak via Stabilization of Ryanodine Receptor in Heart Failure(Development and differentiation-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society
PJ-103 Defective Domain-Domain Interaction within Ryanodine Receptor as a Critical Cause of Diastolic Ca^ Spark in Cardiomyocytes(Excitation-contraction coupling/Ion channel, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
FRS-076 Correction of Defective Inter-Domain Interactions within Ryanodine Recepter by Dantrolene May be a Potent Therapeutic Strategy against Lethal Arrhythmia(Arrhythmia (basic), The 71st Annual Scientific Meeting of the Japanese Circulation Society)
PJ-402 A Domain Which Has a Strong Effect to Stabilize the Ryanodine Receptor Exists inside the Ryanodine Receptor Itself(Heart failure, basic-5 (M) PJ68,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation
PJ-400 β-blocker Ameliorates Intracellular Ca^ Handling in Heart Failure via Correction of Defective Inter-domain Interaction within Ryanodine Receptor(Heart failure, basic-5 (M) PJ68,Poster Session (Japanese),The 70th Anniversary Annual Scientific Me
PJ-175 Defective Inter-domain Interaction within the Ryanodine Recepter Plays a Key Role in the Pathogenesis of Heart Failure(Excitation-contraction coupling/Ion channel-2 (A) PJ30,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting o
OJ-143 Urinary 8-Hydroxy-2' -Deoxyguanosine Level reflects symptomatic status and severity of systolic dysfunction in Patients with Chronic Heart Failure(Heart failure, clinical(05)(M),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the
1 Defective Inter-domain Interaction within the Ryanodine Receptor Underlies a Common Pathogenic Mechanism of Heart Failure and Lethal Arrhythmia(Subcellular Remodeling in the Failing Heart,Symposium 10 (SY-10) (A),The 73rd Annual Scientific Meeting of Th
Differed Ca^ Regulatory Effect of Candesartan or a New Cardioprotective Agent JTV519 on Improvement of Isoproterenol-Induced Dysfunction in Rats
Valsartan Restores Normal FKBP12.6-RyR Interaction by a Strong Inhibition of PKA-Mediated Hyperphosphorylation of RyR in Heart Failure
OJ-019 Dantrolene Stabilizes Domain-Domain Interactions within the Ryanodine Receptor in Failing Hearts(Heart failure, basic-2 (M) OJ4,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
A novel cardioprotective agent, JTV519 improves cardiac function by restoring Ca^ -release function of cardiac sarcoplasmic reticulum in heart failure
Propranolol prevents the development of heart failure by FKBP12.6-mediated stabilization of ryanodine receptor in sarcoplasmic reticulum
FKBP12.6-mediated stabilization of calcium release channel (ryanodine receptor) as a novel therapeutic target in heart failure
Diastereomer-Specific Effects of Double-Stranded Peptides Conjugated with-L-Tyr-L-Phe-or-L-Tyr-D-Phe-Residues on Tyrosine : Phosphorylation and Inhibition of src^NRK, A431, MCF-7, and DU145 Cell Growth
Extrinsic rapid electrical stimulation modulates sarcoplasmic reticulum Ca^ proteins of cultured rat cardiomyocytes
Potent 2,2-Diphenyl-1-picrylhydrazyl Radical-Scavenging Activity of Novel Antioxidants, Double-Stranded Tyrosine Residues Conjugating Pyrocatechol
Assessment of the Brain Areas Perfused by Superselective Intra-arterial Chemotherapy Using Single Photon Emission Computed Tomography with Technetium-99m-Hexamethyl-propyleneamine Oxime : Technical Note
Topological Differences in the Interaction of Human DNA Topoisomerase I with DNA-Histone Complexes Modified by cis- and trans-DDP
Dissociation of DNA from Histone by Reaction of Anti-cancer Drug cis-Diamminedichloroplatinum(II) with DNA-Histone Complexes Used as Cellular Model
Urinary 8-Hydroxy-2'-Deoxyguanosine as a Novel Biomarker for Predicting Cardiac Events and Evaluating the Effectiveness of Carvedilol Treatment in Patients With Chronic Systolic Heart Failure
Low-Dose β-Blocker in Combination With Milrinone Safely Improves Cardiac Function and Eliminates Pulsus Alternans in Patients With Acute Decompensated Heart Failure
Key Role of Chemical Hardness to Compare 2,2-Diphenyl-1-picrylhydrazyl Radical Scavenging Power of Flavone and Flavonol O-Glycoside and C-Glycoside Derivatives

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