Miyata K | Inflammation Research Pharmacology Laboratories Institute For Drug Discovery Research Yamanouchi Pha

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著作論文

Biological Activity of Analogues of YM022. Novel (3-Amino Substituted Phenyl)urea Derivatives of 1,4-Benzodiazepin-2-one as Gastrin : Cholecystokinin-B Receptor Antagonists
In Vivo Pharmacologic Profile of YM158, a New Dual Antagonist for Leukotriene D_4 and Thromboxane A_2 Receptors
Effect of YM158, a Dual Lipid Mediator Antagonist, on Immediate and Late Asthmatic Responses, and on Airway Hyper-responsiveness in Guinea Pigs
Effect of Serotonin (5 - HT)_3 - Receptor Antagonists YM060, YM114 (KAE - 393), Ondasetron and Granisetron on 5 - HT_4 Receptors and Gastric Emptying in Rodents
Protective Effect of a Pancreatic Elastase Inhibitor Against a Variety of Acute Pancreatitis in Rats
Pancreatic Enzyme-Induced Pancreatitis and Systemic Complications in Rats
Species Differences in the 5-Hydroxytryptamine-Induced Contraction in the Isolated Distal Ileum
Characteristics of Inhibitory Effects of Serotonin (5-HT)_3 - Receptor Antagonists, YM060 and YM114 (KAE - 393), on the von Bezold - Jarisch Reflex Induced by 2 - Methyl - 5 - HT, Veratridine and Electrical Stimulation of Vagus Nerves in Anesthetized Rats
Studies on Serotonin (5-HT)_3-Receptor Antagonist Effects of Enantiomers of 4,5,6,7-Tetrahydro-1H-Benzimidazole Derivatives
YM-40461 Improves Airway Clearance in Guinea Pigs with Induced Subacute Bronchitis
YM-40461, a Potent Surfactant Secretagogue, Improves Mucocilliary Clearance in SO_2-Exposed Guinea Pigs
Synthesis of the Selective 5-Hydroxytryptamine 4 (5-HT_4) Receptor Agonist (+)-(S)-2-Chloro-5-methoxy-4-[5-(2-piperidylmethyl)-1,2,4-oxadiazol-3-yl]aniline
Novel 5-Hydroxytryptamine 4 (5-HT_4) Receptor Agonists. Synthesis and Gastroprokinetic Activity of 4-Amino-N-[2-(1-aminocycloalkan-1-yl)ethyl]-5-chloro-2-methoxybenzamides
Novel 5-Hydroxytryptamine (5-HT_3) Receptor Antagonists. Synthesis and Structure-Activity Relationships of 9-Methyl-2,3,4,9-tetrahydrothiopyrano[2,3-b]indol-4-one Derivatives
Novel 5-Hydroxytryptamine (5-HT_3) Receptor Antagonists. IV. Synthesis and Pharmacological Evaluation of the Oxidation Products of (-)-(R)-5-[(1-Methyl-1H-indol-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazole Hydrochloride (YM060 : Ramosetron)
Novel 5-Hydroxytryptamine (5-HT_3) Receptor Antagonists. III. Pharmacological Evaluations and Molecular Modeling Studies of Optically Active 4,5,6,7-Tetrahydro-1H-benzimidazole Derivatives
Novel 5-Hydroxytryptamine (5-HT_3) Receptor Antagonists. II. Synthesis and Structure-Activity Relationships of 4,5,6,7-Tetrahydro-1H-benzimidazole Derivatives
Novel 5-Hydroxytryptamine (5-HT_3) Receptor Antagonists. I. Synthesis and Structure-Activity Relationships of Conformationally Restricted Fused Imidazole Derivatives
Antisecretory and Antiulcer Effects of YM020, a New H^+, K^+-ATPase Inhibitor, in Rats and Dogs
Comparative Evaluation of the Role of Endogenous Gastrin in Basal Acid Secretion in Conscious Rats Provided with Chronic Fistula and Pylorus Ligation

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