Examination of Clinical Efficacy of Keishibukuryogan on Non-Specific Complaints Associated with Varicose Veins of the Lower Extremity
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概要
- 論文の詳細を見る
The subjective symptoms of varicose veins of the lower extremity often include malaise, numbness, coldness, pain, and pruritus of the lower extremity, and relieving these complaints is important in managing the quality of life of patients. We have examined the clinical efficacy of keishibukuryogan, a Kampo prescription for improving oketsu (impaired microcirculation, congestion), on non-specific complaints associated with varicose veins of the lower extremity. Keishibukuryogan was administered to 30 patients with non-specific complaints associated with varicose veins of the lower extremity for 12 weeks, resulting in improvements in the scores of subjective symptoms, severity of varicose veins, and oketsu as well as an increase in skin perfusion pressure. And especially the effect was remarkable in female. In addition, oketsu was shown to be involved in the subjective symptoms associated with varicose veins of the lower extremity, demonstrating efficacy of keishibukuryogan. No adverse drug reaction or abnormal laboratory result was observed in patients receiving keishibukuryogan, and the rate of general improvement and usefulness was 73.3%. It was suggested that keishibukuryogan was useful to improve the symptoms of patients with non-specific complaints associated with varicose veins of the lower extremity especially in female patients. (*English translation of Jpn J Phlebol 2013; 24: 303-310)
- 日本脈管学会、日本血管外科学会、日本静脈学会の論文
著者
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Kitagawa Yuko
Department Of Food Science And Technology School Of Agriculture Nagoya University
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Egawa Tomohisa
Department Of Surgery Saiseikai Kanagawaken Hospital
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Hayashi Shinobu
Department Of Dermatology Shimane Medical University
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Nagashima Atsushi
Department Of Digestive Surgery And Surgical Oncology (surgery Ii) Yamaguchi University Graduate Sch
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Obara Hideaki
Department Of Surgery And Laboratory Tokyo Electric Power Company Hospital
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Ito Yasuhiro
Department Of Cell Differentiation The Sakaguchi Laboratory School Of Medicine Keio University
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Nagashima Atsushi
Department of Surgery (Vascular Surgery), Saiseikai Yokohamashi Tobu Hospital, Yokohama, Kanagawa, Japan
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Shibutani Shintaro
Department of Surgery (Vascular Surgery), Saiseikai Yokohamashi Tobu Hospital, Yokohama, Kanagawa, Japan
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Okubo Hirotoki
Department of Surgery (Vascular Surgery), Saiseikai Yokohamashi Tobu Hospital, Yokohama, Kanagawa, Japan
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Shimogawara Tatsuya
Department of Surgery (Vascular Surgery), Saiseikai Yokohamashi Tobu Hospital, Yokohama, Kanagawa, Japan
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Ichinose Tsuyoshi
Department of Surgery (Vascular Surgery), Saiseikai Yokohamashi Tobu Hospital, Yokohama, Kanagawa, Japan
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Mihara Kouki
Department of Surgery (Vascular Surgery), Saiseikai Yokohamashi Tobu Hospital, Yokohama, Kanagawa, Japan
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Kitagawa Yuko
Department of Surgery, Keio University, Tokyo, Japan
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