Castleman's Disease Accompanied by Hypolipidemic Cerebral Hemorrhage and Nephrosclerosis
スポンサーリンク
概要
- 論文の詳細を見る
A 56-year-old Japanese man developed a cerebral hemorrhage and was diagnosed with plasma cell-type multicentric Castleman's disease (MCD) based on the findings of an inguinal lymph node biopsy in addition to clinical findings, including hypergammaglobulinemia, anemia and elevation of the levels of CRP and serum IL-6. Although a renal biopsy showed nephrosclerosis, the levels of serum lipids and apolipoprotein were low. Following the initiation of treatment with anti-interleukin-6 receptor antibodies, the hypergammaglobulinemia, anemia, CRP level and serum lipid profile improved. However, inflammation due to overproduction of IL-6 persisted, and atherosclerotic vascular events occurred as critical complications, even though the serum levels of lipids were very low.
著者
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Suwabe Tatsuya
Nephrology Center Toranomon Hospital
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Ubara Yoshifumi
Nephrology Center Toranomon Hospital
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Takaichi Kenmei
Nephrology Center Toranomon Hospital
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OOHASHI Kenichi
Department of Pathology, Toranomon Hospital
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Hayami Noriko
Nephrology Center Toranomon Hospital Kajigaya
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Hoshino Junichi
Nephrology Center Toranomon Hospital
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Okubo Minoru
Department Of Endocrinology And Metabolism Okinaka Memorial Institute For Medical Research And Toran
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Hiramatsu Rikako
Nephrology Center Toranomon Hospital Kajigaya
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Fujii Takashi
Department Of Applied Physics And Chemistry The University Of Electro-communications
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Sumida Keiichi
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan
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Mise Koki
Nephrology Center, Toranomon Hospital, Japan
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Hasegawa Eiko
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan
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Yamanouchi Masayuki
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan
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Sawa Naoki
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan
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Imafuku Aya
Nephrology Center, Toranomon Hospital, Japan
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Oga Tatsuhide
Department of Rehabilitation, Toranomon Hospital, Japan
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Ubara Yoshifumi
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan
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Hayami Noriko
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan
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Suwabe Tatsuya
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan
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Okubo Minoru
Department of Endocrinology and Metabolism, Toranomon Hospital, Japan
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