Churg-Strauss Syndrome Presenting with Acute Renal Insufficiency Accompanied by Eosinophilic Tubulointerstitial Nephritis
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概要
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We encountered an unusual and rare case of 59-year-old woman with Churg-Strauss syndrome (CSS) showing myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-related acute renal insufficiency accompanied by eosinophilic tubulointerstitial nephritis. To date, reports in English of CSS presenting with rapidly progressive/acute renal insufficiency and biopsy-proven renal lesions have been uncommon. Here, we discuss this unusual case and review the previously reported CSS cases. The complication of eosinophilic tubulointerstitial nephritis in CSS cases with acute renal insufficiency might be higher than generally thought. Furthermore, the presence of eosinophilic infiltration and eosinophilic tubulointerstitial nephritis might be associated with the good renal outcome in CSS patients.
著者
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Sawa Naoki
Nephrology Center Toranomon Hospital
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Takemoto Fumi
Nephrology Center Toranomon Hospital
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Suwabe Tatsuya
Nephrology Center Toranomon Hospital
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Ubara Yoshifumi
Nephrology Center Toranomon Hospital
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Takaichi Kenmei
Nephrology Center Toranomon Hospital
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YAMANOUCHI Masayuki
Nephrology Center, Toranomon Hospital
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Hayami Noriko
Nephrology Center Toranomon Hospital Kajigaya
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Hoshino Junichi
Nephrology Center Toranomon Hospital
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Hiramatsu Rikako
Nephrology Center Toranomon Hospital Kajigaya
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OHASHI Kenichi
Department of Human Pathology, Graduate School of Medicine, University of Tokyo
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HARA Shigeko
Health Care Center, Toranomon Hospital, Tokyo
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Hara Shigeko
Health Management Center, Toranomon Hospital, Japan
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Sumida Keiichi
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan
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Hasegawa Eiko
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan
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Hirohama Daigoro
Nephrology Center, Toranomon Hospital, Japan
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Yamanouchi Masayuki
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan
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Takemoto Fumi
Nephrology Center, Toranomon Hospital, Japan
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Sawa Naoki
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan
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Ubara Yoshifumi
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan
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Ohashi Kenichi
Department of Pathology, Toranomon Hospital, Japan
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