Anti-Aquaporin-4 Antibody-Seronegative NMO Spectrum Disorder with Baló's Concentric Lesions
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概要
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A 34-year-old woman developed simultaneous bilateral severe optic neuritis and subsequent myelitis. Two months after the first attack, she developed a headache and dysesthesia in the left arm. Brain magnetic resonance imaging revealed multiple hyperintense lesions in the white matter of the right hemisphere, some of which were Baló-like concentric lesions. Our diagnosis was neuromyelitis optica spectrum disorder with Baló's concentric sclerosis (BCS), although the patient was negative for anti-aquaporin-4 (anti-APQ4) antibodies. Our case suggests that Baló's concentric sclerosis overlaps with neuromyelitis optica spectrum disorder and that this overlapping is caused by a mechanism that does not involve anti-AQP4 antibodies.
著者
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Kuwabara Satoshi
Department Of Neurology Chiba University
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Masuda Hiroki
Department Of Applied Chemistry Faculty Of Engineering University Of Miyazaki
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Mori Masahiro
Department Of Cancer Research Research Institute For Nuclear Medicine And Biology Hiroshima Universi
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Masuda Hiroki
Department of Neurology, Narita Red Cross Hospital, Japan
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Katayama Kaoru
Department of Neurology, Narita Red Cross Hospital, Japan
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Kikkawa Yuriko
Department of Neurology, Narita Red Cross Hospital, Japan
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