Correction of Hyponatremia by Tolvaptan Before Left Ventricular Assist Device Implantation
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概要
- 論文の詳細を見る
Hypervolemic hyponatremia is often complicated with advanced heart failure together with increased excretion of sodium by diuretics. Tolvaptan, an oral vasopressin-2-receptor antagonist, has been previously reported to improve congestion and correct hyponatremia through increased excretion of free water. However, there is little evidence concerning the administration of tolvaptan in patients with stage D heart failure. We experienced 2 patients with stage D heart failure who received 3.75 mg/day of tolvaptan to correct hyponatremia before ventricular assist device implantation. It may be useful, even for patients with stage D heart failure, to administer a low dose of tolvaptan to treat hyponatremia before ventricular assist device implantation to avoid a drastic alteration in serum sodium concentration perioperatively.
著者
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Inaba Toshiro
Department Of Cardiology The Cardiovascular Institute
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Kyo Shunei
Department Of Cardiac Surgery Saitama Medical School
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Hirata Yasunobu
Department Of Advanced Clinical Science And Therapeutics Cardiovascular Medicine Graduate School Of
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Shiga Taro
Department Of Cardiovascular Medicine Graduate School Of Medicine The University Of Tokyo
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Ono Minoru
Department Of Anesthesiology Kaizuka City Hospital
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Endo Miyoko
Department Of Bacteriology Tokyo Metropolitan Research Laboratory Of Public Health
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Hatano Masaru
Department Of Cardiology Narita Red Cross Hospital
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Kato Naoko
Department Of Anesthesiology Aichi Gakuin University School Of Dentistry
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Kinugawa Koichiro
Department Of Cardiovascular Medicine Graduate School Of Medicine University Of Tokyo
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Yao Atsushi
Department Of Cardiology Tokyo University Hospital
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Nishimura Takashi
Department Of Animal Science Faculty Of Agriculture Iwate University
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Maki Hisataka
Department Of Cardiovascular Medicine Graduate School Of Medicine University Of Tokyo
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Imamura Teruhiko
Department Of Cardiovascular Medicine Graduate School Of Medicine University Of Tokyo
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Nagai Ryozo
Jichi Medical School
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Kato Naoko
Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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Ono Minoru
Department of Cardiothoracic Surgery, Graduate School of Medicine, The University of Tokyo
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