Rapidly Progressive Cardiac Allograft Vasculopathy in Early Onset Regressed With Everolimus Treatment in an Adult Cardiac Recipient
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概要
- 論文の詳細を見る
A 60-year-old man with severe heart failure underwent an orthotopic heart transplant. Maintenance immunosuppression consisted of a calcineurin inhibitor, mycophenolate mofetil (MMF), and a glucocorticoid. Six months after the transplantation, coronary angiography (CAG) and intravascular ultrasound sonography (IVUS) showed rapidly progressive cardiac allograft vasculopathy (CAV) along with acute cellular rejection. Methylprednisone pulse therapy resulted in the resolution of acute rejection. MMF was exchanged for everolimus (EVL) and 6 months after EVL therapy, CAG and IVUS revealed the regression of CAV. EVL can improve established CAV as well as prevent the progression of CAV.
著者
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Inaba Toshiro
Department Of Cardiology The Cardiovascular Institute
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Kyo Shunei
Department Of Cardiac Surgery Saitama Medical School
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Hirata Yasunobu
Department Of Advanced Clinical Science And Therapeutics Cardiovascular Medicine Graduate School Of
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Shiga Taro
Department Of Cardiovascular Medicine Graduate School Of Medicine The University Of Tokyo
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Ono Minoru
Department Of Anesthesiology Kaizuka City Hospital
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Hatano Masaru
Department Of Cardiology Narita Red Cross Hospital
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Kinugawa Koichiro
Department Of Cardiovascular Medicine Graduate School Of Medicine University Of Tokyo
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Yao Atsushi
Department Of Cardiology Tokyo University Hospital
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Ishida Junichi
Department Of Analytical Chemistry Faculty Of Pharmaceutical Sciences Fukuoka University
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Nishimura Takashi
Department Of Animal Science Faculty Of Agriculture Iwate University
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Maki Hisataka
Department Of Cardiovascular Medicine Graduate School Of Medicine University Of Tokyo
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Imamura Teruhiko
Department Of Cardiovascular Medicine Graduate School Of Medicine University Of Tokyo
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Nagai Ryozo
Jichi Medical School
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