Influence of Sleep-Disorder Breathing on Recurrence in Patients with Catheter Ablation Therapy for Atrial Fibrillation

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概要

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• <B>Background:</B> Previous studies have shown that Sleep-Disorder Breathing (SDB) increased the risk of rhythm disorder including atrial fibrilation (Af). However, there are few data on addressing the influence of SDB on recurrence after catheter ablation (CA) for Af. <B>Methods:</B> 50 patients (38 male, 60±10 years old) with paroxysmal (60%) and persistent (40%) Af who underwent CA were enrolled in this study. All patients had a sleep study with portable monitoring (type 3) for measurement of apnea hypopnea index (AHI). They were divided into two groups according to AHI (Normal group: AHI<5, SDB group: AHI>5). And then, we compared clinical characteristics and recurrence rate of Af after CA between two groups. <B>Result:</B> 29 (58%) patients were categorized into SDB group. The prevalence of hypertension (48% vs 19%, p=0.034) and obesity (BMI: 25.3 vs 22.9, p=0.007) were higher in SDB group. Left atrial diameter (41.2 vs 37.5 mm, p=0.014) were larger in SDB group. After a mean follow-up of 10.9±4.5 months, Af recurrence rate was 24% in normal group and 34% in SDB group (P=0.645). Only one (20%) of 5 patients treated with continuous positive airway pressure in SDB group had recurrence of Af. <B>Conclusion:</B> SDB may increase the recurrence rate of Af after CA and CPAP treatment might be helpful for reduction of Af recurrence.

著者

• Fujiwara Kensuke

  Department of Cardiology, New Tokyo Hospital

• Iwasa Atsushi

  Department Of Cardiology Hirosaki University School Of Medicine

• Fujiwara Kensuke

  Department Of Cardiology New Tokyo Hospital

• Abe Koji

  Department Of Applied Chemistry Graduate School Of Engineering Tohoku University

• Komura Satoru

  Department of Cardiology, New Tokyo Hospital

• Sato Chizuru

  Department of Cardiology, New Tokyo Hospital

• Iwasa Atsushi

  Department of Cardiology, New Tokyo Hospital

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