Non-Contact Mapping of the Origin of Provoked Ventricular Tachycardia in Brugada Syndrome
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概要
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<B>Introduction:</B> We investigated electrophysiological properties of the entire right ventricular (RV) endocardium of provoked ventricular tachycardia/ventricular fibrillation (VT/VF) in 2 patients with Brugada syndrome (BS). <B>Methods:</B> N/A. <B>Results:</B> Case 1. Type 3 Brugada type ECG which changed to type 1 ECG by class Ic antiarrhythmic drug, pilsicainide. Electrophysiologic study (EPS): Double ventricular premature stimuli from RVOT (600/260/200 ms) induced VF. The multielectrode array (Ensite, St. Jude Medical) was placed at the right ventricular outflow tract (RVO) and VF was induced again from RVOT (600/224/180 ms). Non-contact mapping during organized rapid VT before degenerating into VF showed that provoked VT arose from RVOT. Case 2: Type 1 Brugada type ECG. EPS: Triple ventricular premature stimuli from RV apex (600/250/220/200 ms) reproducibly induced VF. Non-contact mapping during organized rapid VT showed that provoked VT arose from RV free wall. <B>Conclusion:</B> RVOT and RV free wall appears to be crucial in the initiation and maintenance of VT with degeneration into VF in BS.
著者
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Kofune Masayoshi
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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Watanabe Ichiro
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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Kasamaki Yuji
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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Kunimoto Satoshi
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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Nagashima Koichi
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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Okumura Yasuo
Division Of Cardiology Department Of Cardiovascular Disease Nihon University School Of Medicine
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Nakai Toshiko
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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Ohkubo Kimie
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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Hirayama Atsushi
Division Of Cardiology Department Of Internal Medicine Nihon University School Of Medicine
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Mano Hiroaki
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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SONODA Kazumasa
Division of Cardiology, Department of Medicine, Nihon University School of Medicine
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