Forming a personal computer database from the Japanese Ministry of Health and Welfare's "Adverse Drug Reaction Monitoring System".

概要

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1. The "Adverse Drug Reaction Monitoring System" has been developed by the Japanese Ministry of Health and Welfare. From 700 to 900 adverse reactions are reported annually. They are not, however, used clinically, since an appropriate computer system has not been established. 2. We have been entering 12, 241 adverse reactions reported in the past 8 years into a personal computer in order to create an adverse drug effects database. 3. The database has enabled fast, accurate retrieval and analysis. 4. There were 2, 863 adverse effects associated with antibiotics. Classification by the chemical structure is more appropriate than by the sensitivity to microorganisms, which was used by the Japanese Ministry of Health and Welfare. 5. In order to compile the database, it was necessary to standardize and classify the drug names and adverse reactions in an appropriate manner. 6. The present goal is to make this database widely available for clinical use.
一般社団法人日本臨床薬理学会の論文