Nuclear magnetic resonance and circular dichroism spectra of 2-(aminomethyl)cyclohexylamine platinum(II) complexes.
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概要
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Six-membered platinum(II) complexes of 2-(aminomethyl)cyclohexylamine (=amcha), whose four isomers are (1<I>R</I>,2<I>R</I>)-, (1<I>S</I>,2<I>S</I>)-, (1<I>R</I>,2<I>S</I>)-, and (l<I>S</I>,2<I>R</I>)-amcha, were synthesized. The conformations of [Pt(en)(l<I>S</I>,2<I>S</I>-amcha)]Cl<SUB>2</SUB>, [Pt(NH<SUB>3</SUB>)<SUB>2</SUB>(1<I>S</I>,2<I>R</I>-amcha)]Cl<SUB>2</SUB>, [Pt(en)(1<I>R</I>,2<I>R</I>-amcha)]Cl<SUB>2</SUB>, and [Pt(NH<SUB>3</SUB>)<SUB>2</SUB>(1<I>R</I>,2<I>R</I>-amcha)]Cl<SUB>2</SUB> were determined by <SUP>1</SUP>H-NMR, <SUP>13</SUP>C-NMR, and CD spectra. It is proposed that [Pt(en)1<I>S</I>,2<I>S</I>-amcha)]Cl<SUB>2</SUB> and [Pt(NH<SUB>3</SUB>)<SUB>2</SUB>(1<I>S</I>,2<I>S</I>-amcha)]Cl<SUB>2</SUB> take a fixed chair form with a dihedral angle (Pt–N–C(1)–C(6)) of 180°, while [Pt(en)(1<I>S</I>,2<I>S</I>-amcha)]Cl<SUB>2</SUB> and [Pt(NH<SUB>3</SUB>)<SUB>2</SUB>(1<I>S</I>,2<I>S</I>-amcha)]Cl<SUB>2</SUB> are interconverting between two chair forms.
- 公益社団法人 日本化学会の論文
著者
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Noji Masahide
Faculty Of Pharmaceutical Sciences Nagoya City University
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Kidani Yoshinori
Faculty Of Pharmaceutical Sciences Nagoya City University
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Okamoto Koji
Faculty of Pharmaceutical Sciences, Nagoya City University
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