Studies on biologically active pteridines. VI. Biopterin conjugated to .BETA.-D-galactosidase and bovine serum albumine.
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概要
- 論文の詳細を見る
4-Hydroxy-6-(L-<I>erythro</I>-1,2-dihydroxypropyl)-2-(methylthio)pteridine was converted by ethylenediamine to 2-(2-aminoethylamino)analogue of biopterin, which condensed with <I>N</I>-hydroxysuccimidyloxy <I>m</I>-maleimidobenzoate to give the maleimidobenzamide. The latter compound and β-D-galactosidase afforded a biopterin-galactosidase conjugate which showed the enzyme activity about 40% as compared to the unmodified enzyme.
- 公益社団法人 日本化学会の論文
著者
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Nagatsu Toshiharu
Laboratory Of Cell Physiology Department Of Life Chemistry Graduate School At Nagatsuta
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Matsuura Sadao
Department Of Chemistry College Of General Education Nagoya University
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Sugimoto Takashi
Department Of Chemical Engineering And Materials Science Faculty Of Engineering Doshisha University
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