A general synthetic approach of spirovetivanes. The synthesis of (.+-.)-solavetivone, (.+-.)-hinesol, and related compounds.
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概要
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The synthetic procedure leading to preparation of representative compounds, (±)-solavetivone and (±)-hinesol, of two classes of spirovetivanes, is described. The procedure involves Diels-Alder reaction of 4-substituted 5,6-dihydro-3,5-dimethylanisoles with methyl acrylate and π-cyclization of 4-(2-mesyloxyethyl)-4-prenyl-2-cyclohexen-1-one as key steps (Scheme 1).
- 公益社団法人 日本化学会の論文
著者
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Murai Akio
Department Of Chemistry Faculty Of Science Hokkaido University
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Masamune Tadashi
Department Of Chemistry Faculty Of Science Hokkaido University
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SATO Shingo
Department of Applied Chemistry, Faculty of Engineering, Aichi Institute of Technology
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