Nucleophilic Ring-Opening of Chlorooxiranes: A New Synthesis of .ALPHA.-Hydroxy .ALPHA.'-Substituted Ketones from Carbonyl Compounds and 1-Chloroalkyl p-Tolyl Sulfoxides.
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概要
- 論文の詳細を見る
The addition of 1-chloroalkyl <I>p</I>-tolyl sulfoxides to carbonyl compounds gave adducts which were then converted to chlorooxiranes in two steps with good overall yields. The treatment of the chlorooxiranes with various nucleophiles gave α-hygroxy α′-substituted ketones or α-hydroxy ketones in good yields.
- 公益社団法人 日本化学会の論文
著者
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Satoh Tsuyoshi
Faculty Of Pharmaceutical Sciences Science University Of Tokyo
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Yamakawa Koji
Faculty Of Pharmaceutical Science Science University Of Tokyo
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Ogura Asako
Faculty of Pharmaceutical Sciences, Science University of Tokyo
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Ikeda Youko
Faculty of Pharmaceutical Sciences, Science University of Tokyo
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