Triethylborane Induced Perfluoroalkylation of Silyl Enol Ethers and Ketene Silyl Acetals with Perfluoroalkyl Iodides.

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概要

• 論文の詳細を見る

• Reaction of perfluoroalkyl iodides with silyl enol ethers mediated by Et<SUB>3</SUB>B in the presence of base such as 2,6-dimethylpyridine provides mixtures of perfluoroalkylated trialkylsilyl enol ethers and α-perfluoroalkylated ketones. The yield and distribution of the products heavily depend on the nature of base employed. Treatment of a reaction mixture consisting of perfluoroalkylated silyl enol ether and α-perfluoroalkylated ketone with coned HCl in THF gives α-perfluoroalkylated ketone as a single product. Reaction of ketene silyl acetals with perfluoroalkyl iodides in the absence of base affords α-perfluoroalkylated esters in excellent yields.

• 公益社団法人 日本化学会の論文

著者

• Miura Katsukiyo

  Department Of Applied Chemistry Graduate School Of Science And Engineering Saitama University

• Utimoto Kiitiro

  Department Of Industrial Chemistry Faculty Of Engineering Kyoto University

• Takeyama Yoshihiro

  Department of Industrial Chemistry, Faculty of Engineering, Kyoto University

• Oshima Koichiro

  Department of Chemistry, Massachusetts Institute of Technology

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