69. 脳血管攣縮による急性期虚血性脳病変に対する高気圧酸素療法の有用性

概要

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Four cases with symptomatic vasospasm which occurred after early operation of aneurysm, were treated by oxygenation at high pressure (OHP). The subjects were limited to the cases 1) who underwent clipping of aneurysm within one week after onset of subarachnoid hemorrhage. 2) whose consciousness level was judged to have aggravated undoubtedly by vasospasm. 3) whose consciousness before aggravation was alert or nearly alert. Results 1) Three cases who was started OHP before falling of consciousness level down to semicoma, obviously recovered. 2) One case who was started OHP after semicomatous stage lasting for 4 days, didn't recover and eventually died. 3) Four other cases who were not treated by OHP didn't recover and finally died. 4) The results indicate that OHP is beneficial as a treatment of cerebral ischemia produced by vasospasm, and also indicate that OHP should be started at the early stage of symptomatic vasospasm.