Comparison of Cell-Mediated Immunity Induced by Three Commercial Single-Dose Mycoplasma hyopneumoniae Bacterins in Pigs

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概要

• 論文の詳細を見る

• This study was to compare the degree of cell-mediated immunity induced by three commercial Mycoplasma hyopneumoniae bacterins using interferon-γ (IFN-γ) measurements, lymphocyte stimulation assays and delayed-type hypersensitivity tests. Serum IFN-γ levels were significantly elevated in all four vaccinated pig groups at 21 days post-vaccination (P<0.05). Lymphocytes isolated 21 days post-vaccination exhibited significantly more proliferation in response to M. hyopneumoniae than lymphocytes isolated 0 day pre-vaccination (P<0.05). Following intradermal injection of M. hyopneumoniae antigen at 14, 21 or 28 days post-vaccination, all pigs in the four vaccinated groups displayed skin reactions characterized by circumscribed, often erythematous nodules. Taken together, these demonstrate that all three commercial single-dose M. hyopneumoniae bacterins used in this study induce varying degrees of cell-mediated immunity.

著者

• Oh Yeonsu

  Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University

• Lee Bog-hieu

  Department Of Food And Nutrition Chung-ang University

• Chae Chanhee

  Department Of Veterinary Pathology College Of Veterinary And School Of Agricultural Biotechnology Se

• Choo Eun

  College of Oriental Medicine, Kyung Hee University

• HAN Kiwon

  Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University

• Kim Sung-Hoon

  College of Oriental Medicine, Kyung Hee University

• KIM Sung-Hoon

  College of Oriental Medicine, Kyunghee University, 1 Hoegi-dong, Dongdaemun-ku, Seoul 130–701, Republic of Korea

• SEO Hwi

  Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea

• CHOO Eun

  College of Oriental Medicine, Kyunghee University, 1 Hoegi-dong, Dongdaemun-ku, Seoul 130–701, Republic of Korea

• PARK Changhoon

  Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea

• HAN Kiwon

  Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea

• HAN Kiwon

  Department of Veterinary Pathology, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University

• CHAE Chanhee

  Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea

• OH Yeonsu

  Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea

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