von Willebrand病の一例

概要

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A case of a seventeen year-old female with von Willebrand's disease was reported. Since childhood, she had noticed hemorrhagic tendency such as purpura, gum bleeding and epistaxis. She had an onset of anemia following melena around late in October, 1967 and was admitted to the hospital on November 16th. Physical examination on admission showed pale skin and purpuras on the extremities, but no enlargement of lymph nodes, liver and spleen. Anemia was severe and bleeding time was remarkably prolonged, but the results of hematological and coagulation tests were quite normal and AHF and PTC were within normal value. The administration of AC-17 resulted in the shortening of bleeding time. From the findings above-mentioned, we assumed this case as a vascular pseudohemophilia, a type of von Willebrand's disease in wide meaning.
学校法人昭和大学・昭和医学会の論文